Patrick J Antonelli, MD
George T. Singleton Professor – Division Of Otology/Neurotology
About Patrick J Antonelli
My name is Patrick Antonelli and I am a professor of Otolaryngology, Neuroscience, and Speech, Language, and Hearing Sciences at the University of Florida. I completed undergraduate, medical school, graduate school, and otolaryngology residency training at the University of Minnesota. After fellowship training in neurotology and skull base surgery at the Michigan Ear Institute, I joined the University of Florida. I served as Chair of Otolaryngology 2004 – 2022 and previously served as assistant dean for clinical informatics and Shands HealthCare Chief Medical Information Officer. I wanted to be a carpenter, but my mother pushed me to attend college. I enjoyed and excelled in biological sciences, leading me to medical school. One chance opportunity after another eventually led me to do research on ear infections. Residency in otolaryngology and fellowship in otology & neurotology were the end result. I am driven to try to improve patient care. This guides my clinical care and research efforts. It also results in a high bar for the residents, fellows, and students that I train. I sincerely want to help patients achieve optimal outcomes with their ear care. I am a fellow of the American Academy of Otolaryngology-Head and Neck Surgery, the American College of Surgeons, the Triological Society, the American Neurotology Society, and the American Otological Society. I am proud to have given over 200 invited scientific presentations. I have also authored over 200 scientific publications and book chapters. I maintain a busy neurotologic practice and an active research program that is focused on otologic implant infections, prevention of iatrogenic hearing loss, ototoxicity, and medication safety. I have been lucky enough to be recognized with numerous awards for teaching, research, and clinical service.
I also enjoy spending time exploring all the world has to offer with my incredible wife & kids, kayaking & paddle-boarding, and tinkering around my home.
Accomplishments
Inductee
2016
·
Best Doctors in America
Invited Speaker
2015
·
5th ENT Conclave 2015, Chennai, India, and Kolkata, India
Best of Oral Abstracts
2014-2015
·
American Academy of Otolaryngology-Head and Neck Surgery Foundation
Best Abstracts
2014
·
Triological Society Combined Sections Meeting
Best of Poster Abstracts
2014
·
American Academy of Otolaryngology-Head and Neck Surgery Foundation
Inductee
2014
·
Doctors of Excellence
Invited Speaker
2014
·
67th Annual General and Scientific Meeting of the New Zealand Society of Otolaryngology, Head and Neck Surgery
Key of Excellence
2014
·
Shands Cancer Service
Top Doctor
2014
·
The Global Directory of Who’s Who
Visiting Professor
2014
·
University of California, Irvine
Visiting Professor
2014
·
University of Louisville
Visiting Professor
2014
·
University of Minnesota
Inductee
2013-2014
·
Best Doctors in America
Honorary member
2013
·
Florida Blue Key
Top Otolaryngologist
2013
·
International Association of Healthcare Professionals
Top Otolaryngologist
2012
·
International Association of Healthcare Professionals
Visiting Professor, James Parkin Lecturer
2012
·
University of Utah School of Medicine
Guest Speaker
2011
·
Michigan Ear Institute Spring Meeting
Visiting Professor
2011
·
Temple University School of Medicine
2nd Place Poster Award
2010
·
Triological Society 2010 Combined Sections Meeting
Best Overall Management Award
2010
·
UFP Annual Management Committee
Head and Neck Surgery Distinguished Service Award
2010
·
American Academy of Otolaryngology
Inductee
2009-2012
·
Best Doctors
Head and Neck Surgery Foundation 2nd Place Poster Award
2009
·
American Academy of Otolaryngology
Inductee
2007-2010
·
America’s Top Physicians
HIPAA Hero Award
2006
·
University of Florida Privacy Office
Otolaryngologist of the Year
2006
·
Network of Florida Otolaryngologists
Physician of Distinction
2006
·
UF Health Shands Hospital
Key of Excellence
2005
·
Shands Customer Service
Visiting Professor
2005
·
Medical College of Georgia
Distinguished Service Award
2004
·
American Academy of Otolaryngology – Head and Neck Surgery
Member
2004
·
Who’s Who in Medical Sciences Education
Visiting Professor
2004
·
Kyushu University Medical School (Japan)
Visiting Professor
2004
·
Eastern Virginia Medical School
Visiting Professor
2004
·
Hyogo University Medical School (Japan)
Visiting Professor
2004
·
Mie University Medical School (Japan)
Visiting Professor
2004
·
Fukuoka University Medical School (Japan)
Shands Star, National Quality Week
2003-2004
·
Shands HealthCare
Visiting Professor
2003
·
UT Southwestern
Inductee
2002-2010
·
Best Doctors in America
Inductee
2002-2003
·
Strathmore’s Who's Who
Inductee
2001-2005
·
America’s Top Doctors
Inductee
2001
·
America’s Best Doctors
Inductee
2001
·
How to Find the Best Doctors: Florida 2000
Visiting Professor
2001
·
University of Michigan
Laptop Computer Award
2000
·
University of Florida
Visiting Professor
2000
·
University of Miami
Inductee
1999
·
Who’s Who in American Business
Inductee
1999
·
Strathmore’s Who’s Who
Merit Award
1999
·
University of Florida
Faculty Research Teacher of the Year Award
1998-2004
·
University of Florida, Department of Otolaryngology
Grant for Auditory Service
1998
·
Warren V. Musser Foundation
Inductee
1998
·
Who’s Who in Medicine and Healthcare
Certificate of Recognition for Community Service
1997
·
Florida Medical Association
Honor Award
1997
·
American Academy of Otolaryngology Head and Neck Surgery
Inductee
1996-1997
·
Best Doctors in America: Southeast Region
Continuous Quality Improvement Team of Distinction Award
1996
·
Shands Hospital
Faculty Teacher of the Year Award
1995
·
University of Florida, Department of Otolaryngology
Melvin E. Sigel Resident Teaching Award
1993
·
University of Minnesota
Research Award
1993
·
Minnesota Society for the Prevention of Blindness and Preservation of Hearing
Albert Hohmann Research Award
1992
·
University of Minnesota
Head and Neck Surgery/ARO Resident Research Award, Second Place in Basic Science
1992
·
American Academy of Otolaryngology
Resident Travel Award
1992
·
Association for Research in Otolaryngology
Research Award
1991
·
Minnesota Society for the Prevention of Blindness and Preservation of Hearing
Inductee
1987
·
Alpha Omega Alpha Honor Society
Inductee
1983
·
Golden Key Honor Society
Teaching Profile
Courses Taught
2019-2020
GMS6705 Functional Human Neuroanatomy
2018
MDC7600 Surgery Clerkship
2018
MDT7590 Elect Top/Otolaryngol
2018
PAS5280 Otolaryngology
2013
GMS6417 Int Aging Physiology
2022-2023
PAS5010 Intro to Medicine 1
Board Certifications
-
Neurotology/OtologyAmerican Board of Otolaryngology
-
OtolaryngologyAmerican Board of Otolaryngology
Clinical Profile
Specialties
- Ear, Nose, and Throat ENT
Subspecialties
- Neurotology
Areas of Interest
- Acoustic neuroma
- Bell palsy
- Brain herniation
- Cholesteatoma
- Cochlear implant
- Ear infection – chronic
- Encephalocele / CSF leak
- Hearing loss
- Ménière disease
- Otitis
- Otitis media with effusion
- Otosclerosis
- Sensorineural deafness
- Tinnitus
- Vertigo-associated disorders
Research Profile
*Prevention and treatment of otologic implant infections *Otologic wound healing *Mechanisms responsible for hearing loss with violation of the inner ear *Prevention of tympanostomy tube occlusion *Prevention of hearing loss from iatrogenic injury and noise *Pathogenesis of Chronic Suppurative Otitis Media *Medication safety
Open Researcher and Contributor ID (ORCID)
0000-0003-2307-3440
Publications
2024
Microbiome and Otic Quinolone Levels Following Tympanoplasty Assessed by Gelatin Sponge Analysis
Otolaryngology–Head and Neck Surgery.
[DOI] 10.1002/ohn.722.
2024
Potential Toxicity of Boric Acid Powder Otic Insufflation
Otolaryngology–Head and Neck Surgery.
170(1):99-102
[DOI] 10.1002/ohn.484.
2023
Cytotoxicity of Tetracyclines in Human Tympanic Membrane Fibroblasts.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.
44(5):520-524
[DOI] 10.1097/MAO.0000000000003867.
[PMID] 37026784.
2023
Quinolone Ear Drops and Achilles Tendon Rupture.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
76(3):e1360-e1368
[DOI] 10.1093/cid/ciac709.
[PMID] 36065683.
2023
Tympanoplasty Healing Outcomes With Use of Postoperative Otic Quinolones.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.
44(7):696-701
[DOI] 10.1097/MAO.0000000000003919.
[PMID] 37367633.
2022
Triangulation of pharmacoepidemiology and laboratory science to tackle otic quinolone safety
Basic & Clinical Pharmacology & Toxicology.
130(S1):75-80
[DOI] 10.1111/bcpt.13668.
[PMID] 34611995.
2021
Association of US Food and Drug Administration Removal of Indications for Use of Oral Quinolones With Prescribing Trends.
JAMA internal medicine.
181(6):808-816
[DOI] 10.1001/jamainternmed.2021.1154.
[PMID] 33871571.
2021
Effects of quinolone and poloxamer otic suspension on rat tympanic membranes.
International journal of pediatric otorhinolaryngology.
147
[DOI] 10.1016/j.ijporl.2021.110805.
[PMID] 34175658.
2021
Efficacy of Topical Epinephrine in Tympanoplasty
The Laryngoscope.
131(10):2319-2322
[DOI] 10.1002/lary.29688.
2021
Generating a Social Media Ontology for Otology and Neurotology.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.
42(5):635-637
[DOI] 10.1097/MAO.0000000000003170.
[PMID] 33935255.
2021
Is Preoperative Computed Tomography Necessary or Useful for Primary Stapes Surgery?
The Laryngoscope.
131(4):703-704
[DOI] 10.1002/lary.28732.
2021
Nanoclay Suspension-Enabled Extrusion Bioprinting of Three-Dimensional Soft Structures
Journal of Manufacturing Science and Engineering-Transactions of the Asme.
143(12)
[DOI] 10.1115/1.4051010.
2020
American Neurotology Society, American Otological Society, and American Academy of Otolaryngology – Head and Neck Foundation Guide to Enhance Otologic and Neurotologic Care During the COVID-19 Pandemic.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.
41(9):1163-1174
[DOI] 10.1097/MAO.0000000000002868.
[PMID] 32925832.
2020
Appropriateness of Otic Quinolone Use among Privately Insured US Patients.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
162(1):102-107
[DOI] 10.1177/0194599819889607.
[PMID] 31743076.
2020
Clinical Practice Guideline: Ménière’s Disease Executive Summary.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
162(4):415-434
[DOI] 10.1177/0194599820909439.
[PMID] 32267820.
2020
Clinical Practice Guideline: Ménière’s Disease.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
162(2_suppl):S1-S55
[DOI] 10.1177/0194599820909438.
[PMID] 32267799.
2020
Cytotoxicity of Ear Drop Excipients in Human and Mouse Tympanic Membrane Fibroblasts.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
162(2):204-210
[DOI] 10.1177/0194599819889701.
[PMID] 31791190.
2020
Diagnosis of Cochlear Implant Infection With Gallium Single-photon Emission Computed Tomography.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.
41(4):e526-e528
[DOI] 10.1097/MAO.0000000000002548.
[PMID] 32176152.
2020
Efficacy of the mini‐meatoplasty
The Laryngoscope.
130(5):1294-1298
[DOI] 10.1002/lary.28186.
2020
Prevalence of occult cochlear basal turn patency
Acta Oto-Laryngologica.
140(11):889-892
[DOI] 10.1080/00016489.2020.1800815.
2020
Rat Model of External Auditory Canal Stenosis.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.
41(7):e876-e880
[DOI] 10.1097/MAO.0000000000002668.
[PMID] 32658405.
2020
Risk for Tympanic Membrane Perforation After Quinolone Ear Drops for Acute Otitis Externa.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
70(6):1103-1109
[DOI] 10.1093/cid/ciz345.
[PMID] 31044229.
2020
The Effects of Steroids on Survival of Mouse and Human Tympanic Membrane Fibroblasts.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
163(2):382-388
[DOI] 10.1177/0194599820912739.
[PMID] 32204660.
2019
Cochlear basal turn patency in unrecognized perilymph gushers
International Journal of Pediatric Otorhinolaryngology.
126
[DOI] 10.1016/j.ijporl.2019.109601.
2019
Commercial Quinolone Ear Drops Cause Perforations in Intact Rat Tympanic Membranes.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.
40(10):1386-1391
[DOI] 10.1097/MAO.0000000000002371.
[PMID] 31592822.
2019
Concomitant Use of Quinolones and Stimulants and the Risk of Adverse Cardiovascular Symptoms: A Retrospective Cohort Study.
Pharmacotherapy.
39(12):1167-1178
[DOI] 10.1002/phar.2343.
[PMID] 31674031.
2019
Microbiome Analysis of Cholesteatoma by Gene Sequencing.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.
40(9):1186-1193
[DOI] 10.1097/MAO.0000000000002355.
[PMID] 31469791.
2019
Prophylactic antibiotics in head and neck free flap surgery: A novel protocol put to the test.
American journal of otolaryngology.
40(6)
[DOI] 10.1016/j.amjoto.2019.102276.
[PMID] 31447185.
2019
Response to the Letter to the Editor: “Ciprofloxacin Otic Suspension and Permanent Peripheral Neuropathy”.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
160(1)
[DOI] 10.1177/0194599818805729.
[PMID] 30798744.
2018
Azithromycin and Sensorineural Hearing Loss in Adults: A Retrospective Cohort Study
Otology & Neurotology.
39(8):957-963
[DOI] 10.1097/MAO.0000000000001887.
[PMID] 29965935.
2018
Cytotoxicity of Ciprofloxacin and Steroids in Mouse Tympanic Membrane Fibroblasts.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
158(3):547-552
[DOI] 10.1177/0194599817751093.
[PMID] 29336207.
2018
Effects of Common Ear Drops on Tympanic Membrane Healing in Rats.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
158(5):917-922
[DOI] 10.1177/0194599818757972.
[PMID] 29460666.
2018
Efficacy of common reagents for killing ticks in the ear canal
Laryngoscope Investigative Otolaryngology.
3(6):492-495
[DOI] 10.1002/lio2.217.
[PMID] 30599035.
2018
Evaluation of Mitoquinone for Protecting Against Amikacin-Induced Ototoxicity in Guinea Pigs.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.
39(1):111-118
[DOI] 10.1097/MAO.0000000000001638.
[PMID] 29194212.
2018
Novel Computed Tomography Findings Suggestive of Perilymph Gusher.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.
39(8):1066-1069
[DOI] 10.1097/MAO.0000000000001916.
[PMID] 30113567.
2018
Prevention and Management of Complications in Otosclerosis Surgery.
Otolaryngologic clinics of North America.
51(2):453-462
[DOI] 10.1016/j.otc.2017.11.015.
[PMID] 29397113.
2018
Prevention of Chlorhexidine Ototoxicity With Poloxamer in Rats.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.
39(8):e738-e742
[DOI] 10.1097/MAO.0000000000001920.
[PMID] 30113566.
2018
Risk of sudden sensorineural hearing loss in adults using phosphodiesterase type 5 inhibitors: Population-based cohort study.
Pharmacoepidemiology and drug safety.
27(6):587-595
[DOI] 10.1002/pds.4405.
[PMID] 29512263.
2018
Use of Systemic Antibiotics for Acute Otitis Externa: Impact of a Clinical Practice Guideline.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.
39(9):1088-1094
[DOI] 10.1097/MAO.0000000000001955.
[PMID] 30124617.
2017
Collagen and α-Tubulin of Mouse Tympanic Membrane Fibroblasts Treated with Quinolones and Aminoglycosides.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
156(2):341-349
[DOI] 10.1177/0194599816672627.
[PMID] 27677596.
2017
Microflora of Retained Intracochlear Electrodes from Infected Cochlear Implants.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
157(1):85-91
[DOI] 10.1177/0194599817693228.
[PMID] 28195822.
2017
Mitochondria-Targeted Antioxidant Mitoquinone Reduces Cisplatin-Induced Ototoxicity in Guinea Pigs.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
156(3):543-548
[DOI] 10.1177/0194599816678381.
[PMID] 28248600.
2017
Quinolone Ear Drops After Tympanostomy Tubes and the Risk of Eardrum Perforation: A Retrospective Cohort Study.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
64(8):1052-1058
[DOI] 10.1093/cid/cix032.
[PMID] 28329128.
2017
Safety and efficacy of ebselen for the prevention of noise-induced hearing loss: a randomised, double-blind, placebo-controlled, phase 2 trial.
Lancet (London, England).
390(10098):969-979
[DOI] 10.1016/S0140-6736(17)31791-9.
[PMID] 28716314.
2017
The Adenoid Microbiome in Recurrent Acute Otitis Media and Obstructive Sleep Apnea.
The journal of international advanced otology.
13(3):333-339
[DOI] 10.5152/iao.2017.4203.
[PMID] 29360088.
2016
Ciprofloxacin Decreases Collagen in Mouse Tympanic Membrane Fibroblasts.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
155(1):127-32
[DOI] 10.1177/0194599816633671.
[PMID] 26932971.
2016
Dietary supplement comprised of β-carotene, vitamin C, vitamin E, and magnesium: failure to prevent music-induced temporary threshold shift.
Audiology and neurotology. Extra.
6(2):20-39
[PMID] 27990155.
2016
Effect of repeated tracheostomy tube reprocessing on biofilm formation.
The Laryngoscope.
126(4):996-9
[DOI] 10.1002/lary.25473.
[PMID] 26267243.
2016
Efficacy of antibiotic prophylaxis prior to tympanoplasty for contaminated cholesteatoma.
The Laryngoscope.
126(10):2363-6
[DOI] 10.1002/lary.26192.
[PMID] 27497428.
2016
Epidemiology of Persistent Tympanic Membrane Perforations Subsequent to Tympanostomy Tubes Assessed With Real World Data.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.
37(9):1376-80
[DOI] 10.1097/MAO.0000000000001195.
[PMID] 27636392.
2016
Magnetic resonance imaging in a guinea pig model of inner ear decompression sickness and barotrauma.
The Laryngoscope.
126(9):2106-9
[DOI] 10.1002/lary.25811.
[PMID] 26649994.
2016
Prevention of biofilm formation by polyquaternary polymer.
International journal of pediatric otorhinolaryngology.
88:157-62
[DOI] 10.1016/j.ijporl.2016.07.004.
[PMID] 27497405.
2016
Randomized Clinical Trial of a Sustained-Exposure Ciprofloxacin for Intratympanic Injection During Tympanostomy Tube Surgery.
The Annals of otology, rhinology, and laryngology.
125(2):105-14
[DOI] 10.1177/0003489415599001.
[PMID] 26296929.
2015
Assessment of mitochondrial membrane potential in HEI-OC1 and LLC-PK1 cells treated with gentamicin and mitoquinone.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
152(4):729-33
[DOI] 10.1177/0194599814564934.
[PMID] 25550222.
2015
Effect of Haemophilus influenzae exposure on Staphylococcus aureus tympanostomy tube attachment and biofilm formation.
JAMA otolaryngology– head & neck surgery.
141(2):148-53
[DOI] 10.1001/jamaoto.2014.3208.
[PMID] 25522126.
2015
Evaluation of apoptotic markers in HEI-OC1 cells treated with gentamicin with and without the mitochondria-targeted antioxidant mitoquinone.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.
36(3):526-30
[DOI] 10.1097/MAO.0000000000000517.
[PMID] 25076226.
2015
Hydrogel sutureless facial nerve repair: pilot clinical investigation.
The Laryngoscope.
125(6):1456-9
[DOI] 10.1002/lary.25072.
[PMID] 25476477.
2015
Perioperative use of antibiotics in otologic procedures.
Current opinion in otolaryngology & head and neck surgery.
23(5):330-3
[DOI] 10.1097/MOO.0000000000000195.
[PMID] 26339962.
2014
Association Between Location of Nasopharyngeal Carcinoma, Pre- and Postradiation Therapy Otitis Media With Effusion, and Sensory Neural Hearing Loss
International Journal of Radiation Oncology Biology Physics.
90(1)
2014
Association Between Location of Nasopharyngeal Carcinoma, Pre- and Postradiation Therapy Otitis Media With Effusion, and Sensory Neural Hearing Loss
International Journal of Radiation Oncology Biology Physics.
90(1)
2014
Mitochondria-targeted antioxidant MitoQ reduces gentamicin-induced ototoxicity.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.
35(3):533-9
[DOI] 10.1097/MAO.0000000000000192.
[PMID] 24518411.
2014
Negative Results Do Not Imply Absence of Ototoxicity with Middle Ear Application of Neomycin.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
151(2)
[DOI] 10.1177/0194599814537033.
[PMID] 25057051.
2014
Utilization Pattern of Phosphodiesterase Type 5 (Pde5) Inhibitors for Erectile Dysfunction Among Commercially Insured Adults in the United States
Pharmacoepidemiology and Drug Safety.
23(1, SI):85-86
2013
Biofilm formation on coated silicone tympanostomy tubes.
International journal of pediatric otorhinolaryngology.
77(2):223-7
[DOI] 10.1016/j.ijporl.2012.10.027.
[PMID] 23200869.
2013
Development of a novel ex vivo porcine skin explant model for the assessment of mature bacterial biofilms.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.
21(5):704-14
[DOI] 10.1111/wrr.12074.
[PMID] 23927831.
2013
Efficacy of disinfecting solutions in removing biofilms from polyvinyl chloride tracheostomy tubes.
The Laryngoscope.
123(1):259-63
[DOI] 10.1002/lary.23612.
[PMID] 22887035.
2013
Microbial flora of cochlear implants by gene pyrosequencing.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.
34(7):e65-71
[DOI] 10.1097/MAO.0b013e3182941101.
[PMID] 23921938.
2013
Response to Letter to the editor regarding Sensorineural hearing loss associated with neomycin eardrops and nonintact tympanic membranes.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
148(6):1061-2
[DOI] 10.1177/0194599813486085.
[PMID] 23690083.
2013
Sensorineural hearing loss associated with neomycin eardrops and nonintact tympanic membranes.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
148(2):277-83
[DOI] 10.1177/0194599812471499.
[PMID] 23264116.
2012
Aminoglycoside Eardrops and Risk of Sensorineural Hearing Loss in Children With Non-Intact Tympanic Membranes
Pharmacoepidemiology and Drug Safety.
21:133-134
2012
Audiology in the sudden hearing loss clinical trial.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.
33(6):907-11
[DOI] 10.1097/MAO.0b013e31825d9a44.
[PMID] 22805100.
2012
Digital music exposure reliably induces temporary threshold shift in normal-hearing human subjects.
Ear and hearing.
33(6):e44-58
[DOI] 10.1097/AUD.0b013e31825f9d89.
[PMID] 22885407.
2012
Effect of tympanostomy tube surface on occlusion.
International journal of pediatric otorhinolaryngology.
76(7):960-2
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[PMID] 22456168.
2012
Effectiveness of pediatric tracheostomy tube cleaning.
Archives of otolaryngology–head & neck surgery.
138(3):251-6
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[PMID] 22351853.
2012
Endolymphatic hydrops perspectives 2012.
Current opinion in otolaryngology & head and neck surgery.
20(5):416-9
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2012
Ototopical neomycin exposure in children with nonintact tympanic membranes.
The Laryngoscope.
122(11):2529-32
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2012
Postradiation Otitis Media With Effusion: Modeling the Complication Probability and Determining the Parameters of Clinical Significance
International Journal of Radiation Oncology Biology Physics.
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2012
Prevention of gentamicin-induced apoptosis with the mitochondria-targeted antioxidant mitoquinone.
The Laryngoscope.
122(11):2543-8
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[PMID] 22965463.
2012
Tympanostomy tube in vitro biofilm potential of common otopathogens.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
146(5):816-22
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[PMID] 22371343.
2011
Biofilm formation on silicone tympanostomy tubes with polyvinylpyrrolidone coating.
Archives of otolaryngology–head & neck surgery.
137(1):19-23
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[PMID] 21242541.
2011
Failure of fluorescence to reveal middle ear penetration of quinolone drops.
Archives of otolaryngology–head & neck surgery.
137(12):1232-5
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[PMID] 22183903.
2011
Oral vs intratympanic corticosteroid therapy for idiopathic sudden sensorineural hearing loss: a randomized trial.
JAMA.
305(20):2071-9
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[PMID] 21610239.
2011
Otologic and audiologic outcomes with the Furlow and von Langenbeck with intravelar veloplasty palatoplasties in unilateral cleft lip and palate.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association.
48(4):412-8
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[PMID] 20536371.
2011
Prospective clinical trial comparing outcome measures between Furlow and von Langenbeck Palatoplasties for UCLP.
Annals of plastic surgery.
66(2):154-63
[DOI] 10.1097/SAP.0b013e3181d60763.
[PMID] 21042188.
2011
Pseudomonas biofilm formation after Haemophilus infection.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
145(3):470-5
[DOI] 10.1177/0194599811405285.
[PMID] 21493260.
2011
Topical antibiotic treatment reduces tympanostomy tube biofilm formation.
The Laryngoscope.
121(5):1067-71
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[PMID] 21437915.
2010
AM-111 prevents hearing loss from semicircular canal injury in otitis media.
The Laryngoscope.
120(1):178-82
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[PMID] 19821539.
2010
Development of a calcium alginate tympanostomy tube.
The Laryngoscope.
120(12):2473-7
[DOI] 10.1002/lary.20981.
[PMID] 21108479.
2010
Errors in the diagnosis and management of necrotizing otitis externa.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
143(4):506-9
[DOI] 10.1016/j.otohns.2010.06.924.
[PMID] 20869559.
2010
Errors in the diagnosis and management of necrotizing otitis externa.
The Laryngoscope.
120 Suppl 4
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[PMID] 21225805.
2010
Perioperative medication errors in otolaryngology.
The Laryngoscope.
120(6):1214-9
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[PMID] 20513042.
2010
Radiation therapy and hearing loss.
International journal of radiation oncology, biology, physics.
76(3 Suppl):S50-7
[DOI] 10.1016/j.ijrobp.2009.04.096.
[PMID] 20171518.
2010
Safety and efficacy of carbomethylcellulose foam in guinea pig middle ear surgery.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
142(3):405-8
[DOI] 10.1016/j.otohns.2009.11.009.
[PMID] 20172389.
2010
Topical dexamethasone and tympanic membrane perforation healing in otitis media: a short-term study.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.
31(3):519-23
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[PMID] 20010446.
2009
Biofilm formation by Pseudomonas aeruginosa on ossicular reconstruction prostheses.
American journal of otolaryngology.
30(6):367-70
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[PMID] 19880023.
2009
Cochlear nerve diameter in normal hearing ears using high-resolution magnetic resonance imaging.
The Laryngoscope.
119(10):2042-5
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2009
Effect of ossicular prosthesis biofilms on middle ear scarring and hearing outcomes.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.
30(8):1191-5
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[PMID] 19779385.
2009
In vitro testing of tympanostomy tube occlusion.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
141(5):598-602
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[PMID] 19861197.
2009
Longitudinal study of growth of children with unilateral cleft-lip palate from birth to two years of age.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association.
46(6):603-9
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2009
Oral Disinhibition Varies With Taster Status: Unilateral Anterior Oral Anesthesia Produces Asymmetric Posterior Taste Loss in Nontasters
Chemical Senses.
34
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Radiation effects on the auditory and vestibular systems.
Otolaryngologic clinics of North America.
42(4):623-34
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[PMID] 19751868.
2008
Effect of blood and mucus on tympanostomy tube biofilm formation.
The Laryngoscope.
118(5):867-70
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2007
Biofilm formation in an in vitro model of cochlear implants with removable magnets.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
136(4):583-8
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2007
Biofilm formation in cochlear implants with cochlear drug delivery channels in an in vitro model.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
136(4):577-82
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2007
Cochlear implant integrity after adenoidectomy with Coblation and monopolar electrosurgery.
American journal of otolaryngology.
28(1):9-12
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2007
Dexamethasone does not alter in vitro antibacterial efficacy of gentamicin.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
136(5):769-72
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2007
Impact of engineered surface microtopography on biofilm formation of Staphylococcus aureus.
Biointerphases.
2(2):89-94
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2007
Ototoxicity after radiotherapy for head and neck tumors.
International journal of radiation oncology, biology, physics.
67(2):469-79
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2006
Alpha1-antitrypsin single dose adjuvant therapy for acute otitis media.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
135(1):111-5
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2006
Hearing loss with stapedotomy and treated otitis media.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
134(4):674-9
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2006
Mitigation of hearing loss from semi-circular canal transection in pseudomonas otitis media with ciprofloxacin-dexamethasone irrigation.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.
27(2):265-9
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2006
Opening plugged tympanostomy tubes: effect of biofilm formation.
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134(1):121-5
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2005
Cochlear implant magnet displacement with minor head trauma.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
133(2):275-7
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2005
Gastric reflux is uncommon in acute post-tympanostomy otorrhea.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
132(4):523-6
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2005
Hearing loss and extent of labyrinthine injury in Pseudomonas otitis media.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
132(1):25-9
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2005
Inflammatory proteases in chronic otitis externa.
The Laryngoscope.
115(4):651-4
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2005
Managing acute otitis media in children with tympanostomy tubes. Panel discussion.
Ear, nose, & throat journal.
84(4 Suppl 2):7-15
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2005
Opening plugged tympanostomy tubes: effect of inner diameter and shaft length.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
132(2):322-6
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2005
Preoperative antibiotic and steroid therapy and hearing loss caused by semicircular canal transection in pseudomonas otitis media.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
132(6):896-901
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2005
Preoperative computed tomography may fail to detect patients at risk for perilymph gusher.
Ear, nose, & throat journal.
84(12):770, 772-4
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2005
Tympanostomy tube otorrhea: treating the first infection. Highlights of a roundtable discussion sponsored by Alcon Laboratories, Inc.; Oct. 16, 2004; Fort Worth, Texas.
Ear, nose, & throat journal.
84(2 Suppl 1):5-15
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2004
A log-normal distribution model of the effect of bacteria and ear fenestration on hearing loss: a Bayesian approach.
Statistics in medicine.
23(3):493-508
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2004
Bacterial biofilms may contribute to persistent cochlear implant infection.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.
25(6):953-7
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2004
Complications of cochlear implant placement with minimal hair shave.
American journal of otolaryngology.
25(2):84-7
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2004
Hearing loss with semicircular canal fistula in exotoxin A-deficient Pseudomonas otitis media.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
130(4):430-6
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2004
Hearing loss with semicircular canal transection and Pseudomonas aeruginosa otitis media.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
131(3):248-52
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2004
Management of acoustic schwannoma.
American journal of otolaryngology.
25(1):38-47
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2003
Alpha 1-antitrypsin and ilomastat inhibit inflammatory proteases present in human middle ear effusions.
The Laryngoscope.
113(8):1347-51
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2003
Cellular telephone use and risk of intratemporal facial nerve tumor.
The Laryngoscope.
113(4):663-7
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2003
Epineurial pseudocysts of the intratemporal facial nerve.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.
24(3):490-3
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2003
Extramedullary hematopoiesis presenting as a middle ear mass.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.
24(6):963-4
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2003
Hearing loss with stapedotomy in otitis media.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
129(6):666-73
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2003
Hyperbaric compression in the guinea pig with perilymph fistula.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
129(3):259-64
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2003
Matrix metalloproteinases in a gerbil cholesteatoma model.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
129(4):402-7
[PMID] 14574296.
2003
Opening plugged tympanostomy tubes: effect of tube composition.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
128(6):870-4
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2003
Protease inhibitors alpha1-antitrypsin and ilomastat are not ototoxic in the chinchilla.
The Laryngoscope.
113(10):1764-9
[PMID] 14520103.
2003
Radiology quiz case 1. Fibromyxoid tumor of the petrous apex.
Archives of otolaryngology–head & neck surgery.
129(1):129, 131-2
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2003
Tympanic membrane metalloproteinase inflammatory response.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
129(6):647-54
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2002
Computerized physician-order entry: are we there yet?
Otolaryngologic clinics of North America.
35(6):1237-43, vii
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2002
Defining tympanostomy tube plugs.
The Laryngoscope.
112(6):951-4
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2002
External auditory canal stenosis after radiation therapy.
The Laryngoscope.
112(11):1975-8
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2002
Fetal central auditory system metabolic response to cochlear implant stimulation.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
127(3):131-7
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2002
Inhibition of matrix metalloproteinases in gerbil cholesteatoma: preliminary findings.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
126(4):404-8
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2002
Opening plugged tympanostomy tubes.
The Laryngoscope.
112(8 Pt 1):1342-5
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2002
Privacy and security of medical information.
Otolaryngologic clinics of North America.
35(6):1203-9, vi
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2002
Radiosurgery for paraganglioma of the temporal bone.
Head & neck.
24(4):384-9
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2002
Skull base fungal osteomyelitis in an immunocompetent host.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
126(1):76-8
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2002
Sympathetic cochleolabyrinthitis in revision stapedectomy surgery.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
126(3):273-80
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2001
Cochlear implant for deafness and blindness from meningitis.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
125(4):403-5
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2001
Definitive radiotherapy in the management of chemodectomas arising in the temporal bone, carotid body, and glomus vagale.
Head & neck.
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2001
Insecticidal activity of common reagents for insect foreign bodies of the ear.
The Laryngoscope.
111(1):15-20
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2001
Magnetic resonance imaging in the search for retrocochlear pathology.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
124(6):652-5
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2001
Middle ear prosthesis displacement in high-strength magnetic fields.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.
22(2):158-61
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2001
Radiology forum: quiz case. Diagnosis: rhabdomyosarcoma with perineural intracranial invasion.
Archives of otolaryngology–head & neck surgery.
127(3):331-2
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2001
Radiotherapy and radiosurgery for skull base tumors.
Otolaryngologic clinics of North America.
34(6):1065-77, viii
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2001
Selective vestibular ablation by KTP laser in endolymphatic hydrops.
The Laryngoscope.
111(6):1057-62
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Treatment of paragangliomas with radiation therapy.
Otolaryngologic clinics of North America.
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Hearing preservation with labyrinthine ablation in otitis media.
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Pneumococcal antibiotic resistance and rates of meningitis in children.
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Canalplasty for chronic tympanic membrane atelectasis.
American journal of otolaryngology.
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1999
Central nervous system metabolic activity after cochlear implantation in the feline neonatal model.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
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1999
Computed tomography and the diagnosis of coalescent mastoiditis.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
120(3):350-4
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1999
Diagnostic yield of high-resolution computed tomography for pediatric sensorineural hearing loss.
The Laryngoscope.
109(10):1642-7
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1999
Impact of resistant pneumococcus on rates of acute mastoiditis.
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121(3):190-4
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Inner ear barotrauma after stapedectomy in the guinea pig.
The Laryngoscope.
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1999
Labyrinthine fenestration in the guinea pig.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
120(3):394-9
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1999
Sensorineural hearing loss after occlusion of the enlarged vestibular aqueduct.
The American journal of otology.
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1999
Stapedectomy in the guinea pig.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
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1999
The effects of kanamycin injection into the fetal lamb cochlea.
Ear, nose, & throat journal.
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1999
Update on vertigo management.
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Early post-laser stapedotomy hearing thresholds.
The American journal of otology.
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1998
Facial palsy from Masson’s vegetant intravascular hemangioendothelioma.
Ear, nose, & throat journal.
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1998
Hearing loss with cochlear modiolar defects and large vestibular aqueducts.
The American journal of otology.
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1998
Intratympanic gentamicin treatment for Meniere’s disease.
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118(5):589-96
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1998
Somatosensory phenomena after multichannel cochlear implantation in prelingually deaf adults.
The American journal of otology.
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1998
The anterior subtemporal, medial transpetrosal approach to the upper basilar artery and ponto-mesencephalic junction.
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1998
Vestibular caloric responses and behavioral state in the fetal sheep.
International journal of pediatric otorhinolaryngology.
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1998
Vestibular function in the fetal sheep.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
118(5):571-5
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1997
CT of the normal suspensory ligaments of the ossicles in the middle ear.
AJNR. American journal of neuroradiology.
18(3):471-7
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1997
Normal and opacified middle ears: CT appearance of the stapes and incudostapedial joint.
Radiology.
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Normal modiolus: CT appearance in patients with a large vestibular aqueduct.
Radiology.
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1997
Temporary threshold shifts induced by low-pass and high-pass filtered noises in fetal sheep in utero.
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1997
Triple semicircular canal occlusion in the guinea pig.
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Bioglass middle ear prosthesis: long-term results.
The American journal of otology.
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Fetal sheep in utero hear through bone conduction.
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1996
Mechanical versus CO2 laser occlusion of the posterior semicircular canal in humans.
The American journal of otology.
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1996
Treatment of chronic tympanic-membrane perforations with a platelet-derived releasate.
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1995
Carbon dioxide laser occlusion of the guinea pig posterior semicircular canal.
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1995
Varicella in immunocompetent children in the first two years of life: role of treatment with oral acyclovir. Italian Acyclovir-Chickenpox Study Group.
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1994
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1994
Tobacco smoke and otitis media in the chinchilla model.
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1993
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Temporal bone pathology in scuba diving deaths.
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[Type A behavioral profile, depression and vascular risk].
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Pseudomonas otitis media after eustachian tube obstruction.
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The significance of experimental animal studies in otitis media.
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Grants
Jan 2021
ACTIVE
CTOA
Role: Principal Investigator
Funding: UNIV OF FLORIDA
Jun 2020
– Jun 2021
Ototoxicity of Next Science Middle Ear Wash in guinea pigs with otitis media
Role: Co-Investigator
Funding: NEXT SCIENCE LLC
Mar 2018
– Nov 2018
Ototoxicity of a Novel Antimicrobial Solution – #2
Role: Principal Investigator
Funding: NEXT SCIENCE LLC
Nov 2017
– Jun 2018
Ototoxicity of a novel antimicrobial solution
Role: Principal Investigator
Funding: NEXT SCIENCE LLC
Jun 2017
– Dec 2021
Ambispective Clinical Evaluation of Sophono (ACES)
Role: Principal Investigator
Funding: MEDTRONIC INC XOMED
Mar 2016
– Dec 2021
MISCELLANEOUS DONORS
Role: Principal Investigator
Funding: MISCELLANEOUS DONORS
Mar 2016
– Oct 2021
A PROSPECTIVE RANDOMIZED DOUBLE BLIND PLACEBO CONTROLLED MULTICENTER PHASE 3 EFFICACY AND SAFETY STUDY OF OTO-104
Role: Principal Investigator
Funding: OTONOMY INC
Feb 2016
– Oct 2022
SAFETY AND EFFICACY OF EXE844 OTIC SUSPENSION IN THE TREATMENT OF OTITIS MEDIA AT TIME OF TYMPANOSTOMY TUBE INSER
Role: Principal Investigator
Funding: ALCON RESEARCH
Dec 2014
– Dec 2016
Assessment of the safety of polyhexamethylene biguanide (PHMB) in the middle ear of chinchilla
Role: Principal Investigator
Funding: MEDTRONIC INC XOMED
Sep 2014
– Sep 2017
A PHASE 2A RANDOMIZED, PLACEBO CONTROLLED, DOUBLE BLIND STUDY OF THE PROTECTIVE EFFECTS OF EPI-743 (VINCERINONE) ON NOISE-INDUCED HEARING LOSS
Role: Principal Investigator
Funding: EDISON PHARMACEUTICALS
Mar 2014
– Mar 2017
A Prospective, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Phase 2b Study of OTO-104 Given as a Single Intratympanic Injection in Subjects with Unilateral Meniere's Disease
Role: Principal Investigator
Funding: RHO INC
via OTONOMY INC
Jul 2009
– May 2021
George T. Singleton Professorship UFF Fund 4458
Role: Principal Investigator
Funding: UF FOUNDATION
Jun 2008
– Jun 2018
Biofilm Analysis of Expanted Cochlear Implants
Role: Principal Investigator
Funding: FL CLINICAL PRACTICE ASSO
Jul 2005
– May 2021
General support of the Department of Otolaryngology. To include research, education, administrative and clinical support. Primarily used to support Resident research and travel
Role: Principal Investigator
Funding: UF FOUNDATION
Jul 2005
– Jun 2020
Semesco Foundation Transferred Funds to support oral, head and neck cancer research
Role: Principal Investigator
Funding: UF FOUNDATION
Education
Fellow, Neurotology & Skull Base Surgery
1993-1994
·
Michigan Ear Institute
Residency – Otolaryngology
1993
·
Fairview – University Medical Center
Internship – Surgery
1989
·
Hennepin County Medical Center
M.S. Clinical Labs
1989
·
University of Minnesota
Medical Degree
1988
·
University of Minnesota
Contact Details
Phones:
- Business:
- (352) 273-5199
Emails:
- Business:
- pa@ufl.edu
Addresses:
- Business Mailing:
-
6201 W. Newberry Road
GAINESVILLE FL 32605 - Business Street:
-
PO Box 100264
1345 CENTER DRIVE M2-228
GAINESVILLE FL 32610