Sang-Joon Ahn

Sang-Joon Ahn

Research Associate Professor

Department: DN-ORAL BIOLOGY
Business Phone: (352) 273-8834
Business Email: zinaahn@ufl.edu

Publications

2020
Acetate and Potassium Modulate the Stationary-Phase Activation of lrgAB in Streptococcus mutans.
Frontiers in microbiology. 11 [DOI] 10.3389/fmicb.2020.00401. [PMID] 32231651.
2020
Understanding LrgAB Regulation of Streptococcus mutans Metabolism.
Frontiers in microbiology. 11 [DOI] 10.3389/fmicb.2020.02119. [PMID] 33013773.
2020
The Pta-AckA Pathway Regulates LrgAB-Mediated Pyruvate Uptake in Streptococcus mutans.
Microorganisms. 8(6) [DOI] 10.3390/microorganisms8060846. [PMID] 32512841.
2020
Regulation of cid and lrg expression by CodY in Streptococcus mutans.
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2020
Characterization of the Streptococcus mutans SMU.1703c-SMU.1702c Operon Reveals Its Role in Riboflavin Import and Response to Acid Stress.
Journal of bacteriology. 203(2) [DOI] 10.1128/JB.00293-20. [PMID] 33077636.
2020
Peptides encoded in the Streptococcus mutans RcrRPQ operon are essential for thermotolerance.
Microbiology (Reading, England). 166(3):306-317 [DOI] 10.1099/mic.0.000887. [PMID] 31935187.
2020
Environmental Triggers of lrgA Expression in Streptococcus mutans.
Frontiers in microbiology. 11 [DOI] 10.3389/fmicb.2020.00018. [PMID] 32047487.
2020
Regulation of cid and lrg expression by CodY in Streptococcus mutans.
MicrobiologyOpen. 9(7) [DOI] 10.1002/mbo3.1040. [PMID] 32282137.
2019
Characterization of LrgAB as a stationary phase-specific pyruvate uptake system in Streptococcus mutans.
BMC microbiology. 19(1) [DOI] 10.1186/s12866-019-1600-x. [PMID] 31606034.
2019
Genomic instability of TnSMU2 contributes to Streptococcus mutans biofilm development and competence in a cidB mutant.
MicrobiologyOpen. 8(12) [DOI] 10.1002/mbo3.934. [PMID] 31599128.
2019
Regulation of cid and lrg expression by CcpA in Streptococcus mutans.
Microbiology (Reading, England). 165(1):113-123 [DOI] 10.1099/mic.0.000744. [PMID] 30475201.
2017
Oxidative Stressors Modify the Response of Streptococcus mutans to Its Competence Signal Peptides.
Applied and environmental microbiology. 83(22) [DOI] 10.1128/AEM.01345-17. [PMID] 28887419.
2017
Remodeling of the Streptococcus mutans proteome in response to LrgAB and external stresses.
Scientific reports. 7(1) [DOI] 10.1038/s41598-017-14324-w. [PMID] 29070798.
2017
Rna-Seq Reveals Enhanced Sugar Metabolism in Streptococcus Mutans Co-Cultured With Candida Albicans Within Mixed-Species Biofilms
Frontiers in Microbiology. 8 [DOI] 10.3389/fmicb.2017.01036.
2017
Modification of the Streptococcus mutans transcriptome by LrgAB and environmental stressors.
Microbial genomics. 3(2) [DOI] 10.1099/mgen.0.000104. [PMID] 28348880.
2016
A Highly Arginolytic Streptococcus Species That Potently Antagonizes Streptococcus mutans.
Applied and environmental microbiology. 82(7):2187-201 [DOI] 10.1128/AEM.03887-15. [PMID] 26826230.
2016
An Essential Role for (p)ppGpp in the Integration of Stress Tolerance, Peptide Signaling, and Competence Development in Streptococcus mutans.
Frontiers in microbiology. 7 [DOI] 10.3389/fmicb.2016.01162. [PMID] 27516759.
2016
Effects of Carbohydrate Source on Genetic Competence in Streptococcus mutans.
Applied and environmental microbiology. 82(15):4821-4834 [DOI] 10.1128/AEM.01205-16. [PMID] 27260355.
2016
Understanding the Streptococcus mutans Cid/Lrg System through CidB Function.
Applied and environmental microbiology. 82(20):6189-6203 [PMID] 27520814.
View on: PubMed
2015
A unique open reading frame within the comX gene of Streptococcus mutans regulates genetic competence and oxidative stress tolerance.
Molecular microbiology. 96(3):463-82 [DOI] 10.1111/mmi.12948. [PMID] 25620525.
2015
Bidirectional signaling in the competence regulatory pathway of Streptococcus mutans.
FEMS microbiology letters. 362(19) [DOI] 10.1093/femsle/fnv159. [PMID] 26363019.
2015
Genetics and Physiology of Acetate Metabolism by the Pta-Ack Pathway of Streptococcus mutans.
Applied and environmental microbiology. 81(15):5015-25 [DOI] 10.1128/AEM.01160-15. [PMID] 25979891.
2015
Regulation of competence and gene expression in Streptococcus mutans by the RcrR transcriptional regulator.
Molecular oral microbiology. 30(2):147-159 [DOI] 10.1111/omi.12079. [PMID] 25146832.
2015
Sharply Tuned pH Response of Genetic Competence Regulation in Streptococcus mutans: a Microfluidic Study of the Environmental Sensitivity of comX.
Applied and environmental microbiology. 81(16):5622-31 [DOI] 10.1128/AEM.01421-15. [PMID] 26070670.
2015
Pluronics-Formulated Farnesol Promotes Efficient Killing and Demonstrates Novel Interactions with Streptococcus mutans Biofilms.
PloS one. 10(7) [DOI] 10.1371/journal.pone.0133886. [PMID] 26222384.
2014
Discovery of novel peptides regulating competence development in Streptococcus mutans.
Journal of bacteriology. 196(21):3735-45 [DOI] 10.1128/JB.01942-14. [PMID] 25135217.
2014
Growth Phase and Ph Influence Peptide Signaling for Competence Development in Streptococcus Mutans
Journal of bacteriology. 196(2):227-236 [DOI] 10.1128/JB.00995-13. [PMID] 24163340.
2013
Evolutionary and Population Genomics of the Cavity Causing Bacteria Streptococcus Mutans
Molecular Biology and Evolution. 30(4):881-893 [DOI] 10.1093/molbev/mss278. [PMID] 23228887.
2012
Identification of the Streptococcus mutans LytST two-component regulon reveals its contribution to oxidative stress tolerance.
BMC microbiology. 12 [DOI] 10.1186/1471-2180-12-187. [PMID] 22937869.
2012
Microfluidic study of competence regulation in Streptococcus mutans: environmental inputs modulate bimodal and unimodal expression of comX.
Molecular microbiology. 86(2):258-72 [DOI] 10.1111/j.1365-2958.2012.08187.x. [PMID] 22845615.
2012
Transcriptional organization and physiological contributions of the relQ operon of Streptococcus mutans.
Journal of bacteriology. 194(8):1968-78 [DOI] 10.1128/JB.00037-12. [PMID] 22343297.
2011
A transcriptional regulator and ABC transporters link stress tolerance, (p)ppGpp, and genetic competence in Streptococcus mutans.
Journal of bacteriology. 193(4):862-74 [DOI] 10.1128/JB.01257-10. [PMID] 21148727.
2010
The Streptococcus mutans Cid and Lrg systems modulate virulence traits in response to multiple environmental signals.
Microbiology (Reading, England). 156(Pt 10):3136-3147 [DOI] 10.1099/mic.0.039586-0. [PMID] 20671018.
2010
Biofilm Formation and Virulence Expression By Streptococcus Mutans Are Altered When Grown in Dual-Species Model
BMC microbiology. 10 [DOI] 10.1186/1471-2180-10-111. [PMID] 20398271.
2009
Changes in biochemical and phenotypic properties of Streptococcus mutans during growth with aeration.
Applied and environmental microbiology. 75(8):2517-27 [DOI] 10.1128/AEM.02367-08. [PMID] 19251884.
2009
Opportunities for disrupting cariogenic biofilms.
Advances in Dental Research. 21(1):17-20 [DOI] 10.1177/0895937409335593. [PMID] 19710079.
2008
Characteristics of biofilm formation by Streptococcus mutans in the presence of saliva.
Infection and immunity. 76(9):4259-68 [DOI] 10.1128/IAI.00422-08. [PMID] 18625741.
2007
Effects of oxygen on biofilm formation and the AtlA autolysin of Streptococcus mutans.
Journal of bacteriology. 189(17):6293-302 [PMID] 17616606.
View on: PubMed
2007
Effects of oxygen on virulence traits of Streptococcus mutans.
Journal of bacteriology. 189(23):8519-27 [PMID] 17921307.
View on: PubMed
2006
Multilevel control of competence development and stress tolerance in Streptococcus mutans UA159.
Infection and immunity. 74(3):1631-42 [PMID] 16495534.
View on: PubMed
2006
The atlA operon of Streptococcus mutans: role in autolysin maturation and cell surface biogenesis.
Journal of bacteriology. 188(19):6877-88 [PMID] 16980491.
View on: PubMed
2005
A hypothetical protein of Streptococcus mutans is critical for biofilm formation.
Infection and immunity. 73(5):3147-51 [PMID] 15845523.
View on: PubMed
2005
Role of HtrA in growth and competence of Streptococcus mutans UA159.
Journal of bacteriology. 187(9):3028-38 [PMID] 15838029.
View on: PubMed

Grants

Apr 2016 ACTIVE
Streptococcus mutans adaptation to oxidative stress by the Cid/Lrg system
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDCR
Apr 2014 – Mar 2017
Regulation of Streptococcus mutans AtlA on the cell surface
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDCR

Teaching Profile

Courses Taught
2018
PHY7979 Advanced Research

Contact Details

Phones:
Business:
(352) 273-8834
Emails:
Business:
zinaahn@ufl.edu