Mary Ellen Davey

Mary Ellen Davey,

Courtesy Associate Professor

Department: DN-ORAL BIOLOGY
Business Phone: (352) 273-8858
Business Email: mdavey@dental.ufl.edu

Teaching Profile

Courses Taught
2013-2022
DEN5127 Infectious Diseases
2017-2020
GMS6193 Research Conference in Oral Biology
2015-2016,2018
DEN8290 Special Topics
2018,2021-2022
GMS5905 Special Topics in Biomedical Sciences
2018
GMS7980 Research for Doctoral Dissertation
2018
GMS7979 Advanced Research
2016-2018
GMS6121 Infectious Diseases
2016
DEN5210 Dev Biol Psychosoc 1
2014,2016
DEN6681 Craniofacial Pathobiology
2014-2015
DEN6251 Clin Manage Dent Pain
2014-2015
DEN6680 Principles and Craniofacial Biology and Emerging Therapies

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0001-8129-0537

Publications

2024
Inhibition of SARS-CoV-2 infection by Porphyromonas gingivalis and the oral microbiome.
bioRxiv : the preprint server for biology. [DOI] 10.1101/2024.02.27.582258. [PMID] 38464164.
2023
Growth of Porphyromonas gingivalis on human serum albumin triggers programmed cell death.
Journal of oral microbiology. 15(1) [DOI] 10.1080/20002297.2022.2161182. [PMID] 36570975.
2023
Lipidomic analysis of Porphyromonas gingivalis reveals novel glycerol bisphosphoceramide, phosphatidyl-, and phosphoglycerol dipeptide lipid families
Journal of Lipid Research. 64(12) [DOI] 10.1016/j.jlr.2023.100470. [PMID] 37924978.
2022
Characterization of a Bacterial Kinase That Phosphorylates Dihydrosphingosine to Form dhS1P
Microbiology Spectrum. 10(2) [DOI] 10.1128/spectrum.00002-22. [PMID] 35286133.
2022
Cortisol Promotes Surface Translocation of Porphyromonas gingivalis
Pathogens. 11(9) [DOI] 10.3390/pathogens11090982. [PMID] 36145414.
2021
A Novel Regulation of K-antigen Capsule Synthesis in Porphyromonas gingivalis Is Driven by the Response Regulator PG0720-Directed Antisense RNA.
Frontiers in oral health. 2 [DOI] 10.3389/froh.2021.701659. [PMID] 35048039.
2021
A Porphyromonas gingivalis Capsule-Conjugate Vaccine Protects From Experimental Oral Bone Loss.
Frontiers in oral health. 2 [DOI] 10.3389/froh.2021.686402. [PMID] 35048031.
2021
Metabolic plasticity enables lifestyle transitions of Porphyromonas gingivalis
npj Biofilms and Microbiomes. 7(1) [DOI] 10.1038/s41522-021-00217-4. [PMID] 34031416.
2021
PPAD Activity Promotes Outer Membrane Vesicle Biogenesis and Surface Translocation by Porphyromonas gingivalis
Journal of Bacteriology. 203(4) [DOI] 10.1128/jb.00343-20.
2021
Serine/Glycine Lipid Recovery in Lipid Extracts From Healthy and Diseased Dental Samples: Relationship to Chronic Periodontitis.
Frontiers in oral health. 2 [DOI] 10.3389/froh.2021.698481. [PMID] 35048038.
2021
Sphingolipid-Containing Outer Membrane Vesicles Serve as a Delivery Vehicle To Limit Macrophage Immune Response to Porphyromonas gingivalis
Infection and Immunity. 89(4) [DOI] 10.1128/iai.00614-20.
2020
Porphyromonas gingivalis Sphingolipid Synthesis Limits the Host Inflammatory Response.
Journal of dental research. 99(5):568-576 [DOI] 10.1177/0022034520908784. [PMID] 32105543.
2020
Synthesis of ppGpp impacts type IX secretion and biofilm matrix formation in Porphyromonas gingivalis.
NPJ biofilms and microbiomes. 6(1) [DOI] 10.1038/s41522-020-0115-4. [PMID] 32005827.
2019
Amino acids as wetting agents: surface translocation by Porphyromonas gingivalis.
The ISME journal. 13(6):1560-1574 [DOI] 10.1038/s41396-019-0360-9. [PMID] 30783212.
2019
Citrullination mediated by PPAD constrains biofilm formation in P. gingivalis strain 381.
NPJ biofilms and microbiomes. 5(1) [DOI] 10.1038/s41522-019-0081-x. [PMID] 32029738.
2019
Galactose Impacts the Size and Intracellular Composition of the Asaccharolytic Oral Pathobiont Porphyromonas gingivalis.
Applied and environmental microbiology. 85(4) [DOI] 10.1128/AEM.02268-18. [PMID] 30552185.
2017
Alterations in oral bacterial communities are associated with risk factors for oral and oropharyngeal cancer.
Scientific reports. 7(1) [DOI] 10.1038/s41598-017-17795-z. [PMID] 29247187.
2017
Natural antigenic differences in the functionally equivalent extracellular DNABII proteins of bacterial biofilms provide a means for targeted biofilm therapeutics.
Molecular oral microbiology. 32(2):118-130 [DOI] 10.1111/omi.12157. [PMID] 26988714.
2016
Synthesis of Sphingolipids Impacts Survival of Porphyromonas gingivalis and the Presentation of Surface Polysaccharides.
Frontiers in microbiology. 7 [PMID] 27965646.
2015
Deletion of a 77-base-pair inverted repeat element alters the synthesis of surface polysaccharides in Porphyromonas gingivalis.
Journal of bacteriology. 197(7):1208-20 [DOI] 10.1128/JB.02589-14. [PMID] 25622614.
2014
A biochemical analysis of the interaction of Porphyromonas gingivalis HU PG0121 protein with DNA.
PloS one. 9(3) [DOI] 10.1371/journal.pone.0093266. [PMID] 24681691.
2013
Arginine deiminase inhibits Porphyromonas gingivalis surface attachment.
Microbiology (Reading, England). 159(Pt 2):275-285 [DOI] 10.1099/mic.0.062695-0. [PMID] 23242802.
2013
Porphyromonas gingivalis: keeping the pathos out of the biont.
Journal of oral microbiology. 5 [DOI] 10.3402/jom.v5i0.19804. [PMID] 23565326.
2013
The nucleoid-associated protein HU╬▓ affects global gene expression in Porphyromonas gingivalis.
Microbiology (Reading, England). 159(Pt 2):219-229 [DOI] 10.1099/mic.0.061002-0. [PMID] 23175503.
2010
A streptococcal effector protein that inhibits Porphyromonas gingivalis biofilm development.
Microbiology (Reading, England). 156(Pt 11):3469-3477 [DOI] 10.1099/mic.0.042671-0. [PMID] 20705665.
2010
HU protein affects transcription of surface polysaccharide synthesis genes in Porphyromonas gingivalis.
Journal of bacteriology. 192(23):6217-29 [DOI] 10.1128/JB.00106-10. [PMID] 20889748.
2008
Tracking dynamic interactions during plaque formation.
Journal of bacteriology. 190(24):7869-70 [DOI] 10.1128/JB.01344-08. [PMID] 18849426.
2006
Enhanced biofilm formation and loss of capsule synthesis: deletion of a putative glycosyltransferase in Porphyromonas gingivalis.
Journal of bacteriology. 188(15):5510-23 [PMID] 16855241.
2006
Molecular genetics analyses of biofilm formation in oral isolates.
Periodontology 2000. 42:13-26 [PMID] 16930303.
2006
Techniques for the growth of Porphyromonas gingivalis biofilms.
Periodontology 2000. 42:27-35 [PMID] 16930304.
2003
Rhamnolipid surfactant production affects biofilm architecture in Pseudomonas aeruginosa PAO1.
Journal of bacteriology. 185(3):1027-36 [PMID] 12533479.

Grants

Jul 2021 ACTIVE
Microbial sphingolipids and suppression of host inflammation in periodontal disease
Role: Project Manager
Funding: NATL INST OF HLTH NIDCR
Jul 2021 – Aug 2022
L-Arg availability affects the physiological state of porphyromonas gingivalis
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDCR
Apr 2019 – Mar 2022
Effect of SutroVax cocktail on Porphyromonas gingivalis biofilm formation and gene expression
Role: Principal Investigator
Funding: VAXCYTE
Jan 2018 – Dec 2019
Determining how PPAD modulates Porphyromonas gingivalis biofilm development
Role: Other
Funding: NATL INST OF HLTH NIDCR
Jun 2017 – Oct 2021
Identification of Fecal Bacteria with Anti-Clostridium difficile Activities
Role: Faculty
Funding: UF DSR OPPORTUNITY FUND
Nov 2015 – Jan 2021
Miscellaneous Donors
Role: Principal Investigator
Funding: MISCELLANEOUS DONORS
Sep 2015 – Aug 2022
Regulatory Mechanisms Controlling Expression of P. gingivalis Surface Structures
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDCR
Apr 2015 – Jun 2021
L-Arg Availability Affects the Physiological State of Porphyromonas gingivalis
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDCR
Sep 2014 – Aug 2016
Identification of mRNA targets of small regulatory RNAs in P. gingivalis
Role: Principal Investigator
Funding: UNIV OF IDAHO via NATL INST OF HLTH NIDCR
Jan 2013 – Dec 2017
Start up funding for Dr. Mary Ellen Davey,Oral Biology
Role: Principal Investigator
Funding: UF COLLEGE OF DENTISTRY SEED PROGRAM

Contact Details

Phones:
Business:
(352) 273-8858
Emails:
Addresses:
Business Mailing:
PO Box 100424
GAINESVILLE FL 32610
Business Street:
ROOM D4-38C
1395 CENTER DRIVE
DEPARTMENT OF ORAL BIOLOGY, COLLEGE OF DENTI
GAINESVILLE FL 32610-0001