Paul A Gulig

Paul A Gulig

Professor

Department: Molecular Genetics & Microbiology
Business Phone: (352) 294-5544
Business Email: gulig@ufl.edu

Publications

2019
Corrigendum: Phylogeny of Vibrio vulnificus From the Analysis of the Core-Genome: Implications for Intra-Species Taxonomy.
Frontiers in microbiology. 10 [DOI] 10.3389/fmicb.2019.01904. [PMID] 31481942.
2019
Detection of Virulence Plasmid-Encoded Genes in Salmonella Typhimurium and Salmonella Kentucky Isolates Recovered from Commercially Processed Chicken Carcasses.
Journal of food protection. 82(8):1364-1368 [DOI] 10.4315/0362-028X.JFP-18-552. [PMID] 31322922.
2018
Relative Contributions of Halobacteriovorax and Bacteriophage to Bacterial Cell Death under Various Environmental Conditions.
mBio. 9(4) [DOI] 10.1128/mBio.01202-18. [PMID] 30087166.
2017
Phylogeny of Vibrio vulnificus from the Analysis of the Core-Genome: Implications for Intra-Species Taxonomy.
Frontiers in microbiology. 8 [DOI] 10.3389/fmicb.2017.02613. [PMID] 29358930.
2017
The Opportunistic Pathogen Vibrio vulnificus Produces Outer Membrane Vesicles in a Spatially Distinct Manner Related to Capsular Polysaccharide.
Frontiers in microbiology. 8 [DOI] 10.3389/fmicb.2017.02177. [PMID] 29163452.
2015
Hepcidin-induced hypoferremia is a critical host defense mechanism against the siderophilic bacterium Vibrio vulnificus.
Cell host & microbe. 17(1):47-57 [DOI] 10.1016/j.chom.2014.12.001. [PMID] 25590758.
2013
Bacterial Impermeability of a Fireproof Fabric
Anesthesia and Analgesia. 116(1)
2011
Genotype is correlated with but does not predict virulence of Vibrio vulnificus biotype 1 in subcutaneously inoculated, iron dextran-treated mice.
Infection and immunity. 79(3):1194-207 [DOI] 10.1128/IAI.01031-10. [PMID] 21199909.
2011
Visual analytics of surveillance data on foodborne vibriosis, United States, 1973-2010.
Environmental health insights. 5:71-85 [DOI] 10.4137/EHI.S7806. [PMID] 22174586.
2010
Genetic characterization of Vibrio vulnificus strains from tilapia aquaculture in Bangladesh.
Applied and environmental microbiology. 76(14):4890-5 [DOI] 10.1128/AEM.00636-10. [PMID] 20495047.
2010
Role of GacA in virulence of Vibrio vulnificus.
Microbiology (Reading, England). 156(Pt 12):3722-3733 [DOI] 10.1099/mic.0.043422-0. [PMID] 20817642.
2010
SOLiD sequencing of four Vibrio vulnificus genomes enables comparative genomic analysis and identification of candidate clade-specific virulence genes.
BMC genomics. 11 [DOI] 10.1186/1471-2164-11-512. [PMID] 20863407.
2009
Roles of RseB, sigmaE, and DegP in virulence and phase variation of colony morphotype of Vibrio vulnificus.
Infection and immunity. 77(9):3768-81 [DOI] 10.1128/IAI.00205-09. [PMID] 19564391.
2009
USER friendly cloning coupled with chitin-based natural transformation enables rapid mutagenesis of Vibrio vulnificus.
Applied and environmental microbiology. 75(15):4936-49 [DOI] 10.1128/AEM.02564-08. [PMID] 19502446.
2009
Phase variation, capsular polysaccharide, pilus and flagella contribute to uptake of Vibrio vulnificus by the Eastern oyster (Crassostrea virginica).
Environmental microbiology. 11(8):1934-44 [DOI] 10.1111/j.1462-2920.2009.01916.x. [PMID] 19689704.
2008
Regulation of fatty acid metabolism by FadR is essential for Vibrio vulnificus to cause infection of mice.
Journal of bacteriology. 190(23):7633-44 [DOI] 10.1128/JB.01016-08. [PMID] 18835990.
2006
Use of a marker plasmid to examine differential rates of growth and death between clinical and environmental strains of Vibrio vulnificus in experimentally infected mice.
Molecular microbiology. 61(2):310-23 [PMID] 16856938.
View on: PubMed
2005
Molecular Pathogenesis of Vibrio vulnificus.
Journal of microbiology (Seoul, Korea). 43 Spec No:118-31 [PMID] 15765065.
View on: PubMed
2004
Ultrasensitive detection of biomolecules with fluorescent dye-doped nanoparticles.
Analytical biochemistry. 334(1):135-44 [PMID] 15464962.
View on: PubMed
2003
Analysis of Vibrio vulnificus from market oysters and septicemia cases for virulence markers.
Applied and environmental microbiology. 69(7):4006-11 [PMID] 12839775.
View on: PubMed
2003
CapG(-/-) mice have specific host defense defects that render them more susceptible than CapG(+/+) mice to Listeria monocytogenes infection but not to Salmonella enterica serovar Typhimurium infection.
Infection and immunity. 71(11):6582-90 [PMID] 14573680.
View on: PubMed
2002
Bacteriophages: potential treatment for bacterial infections.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy. 16(1):57-62 [PMID] 11909002.
View on: PubMed
2002
Phage therapy of local and systemic disease caused by Vibrio vulnificus in iron-dextran-treated mice.
Infection and immunity. 70(11):6251-62 [PMID] 12379704.
View on: PubMed
2001
Virulence plasmid-borne spvB and spvC genes can replace the 90-kilobase plasmid in conferring virulence to Salmonella enterica serovar Typhimurium in subcutaneously inoculated mice.
Journal of bacteriology. 183(15):4652-8 [PMID] 11443102.
View on: PubMed
2000
Constitutively expressed phoP inhibits mouse-virulence of Salmonella typhimurium in an Spv-dependent manner.
Microbiology and immunology. 44(6):447-54 [PMID] 10941927.
View on: PubMed
2000
Construction and phenotypic evaluation of a Vibrio vulnificus vvpE mutant for elastolytic protease.
Infection and immunity. 68(9):5096-106 [PMID] 10948131.
View on: PubMed
2000
Pathogenesis of infection by clinical and environmental strains of Vibrio vulnificus in iron-dextran-treated mice.
Infection and immunity. 68(10):5785-93 [PMID] 10992486.
View on: PubMed
2000
Role of the Salmonella abortusovis virulence plasmid in the infection of BALB/c mice.
FEMS microbiology letters. 188(1):15-8 [PMID] 10867227.
View on: PubMed
1999
Growth of Staphylococcus aureus in Diprivan and Intralipid: implications on the pathogenesis of infections.
Anesthesiology. 91(5):1394-400 [PMID] 10551591.
View on: PubMed
1998
Regulation of the spvR gene of the Salmonella typhimurium virulence plasmid during exponential-phase growth in intracellular salts medium and at stationary phase in L broth.
Microbiology (Reading, England). 144 ( Pt 7):1823-33 [PMID] 9695915.
View on: PubMed
1998
Analysis of host cells associated with the Spv-mediated increased intracellular growth rate of Salmonella typhimurium in mice.
Infection and immunity. 66(6):2471-85 [PMID] 9596705.
View on: PubMed
1997
Exponential-phase expression of spvA of the Salmonella typhimurium virulence plasmid: induction in intracellular salts medium and intracellularly in mice and cultured mammalian cells.
Microbiology (Reading, England). 143 ( Pt 12):3827-39 [PMID] 9421907.
View on: PubMed
1997
Systemic infection of mice by wild-type but not Spv- Salmonella typhimurium is enhanced by neutralization of gamma interferon and tumor necrosis factor alpha.
Infection and immunity. 65(12):5191-7 [PMID] 9393815.
View on: PubMed
1996
Epidural catheter reconnection. Safe and unsafe practice.
Anesthesiology. 85(4):883-8 [PMID] 8873560.
View on: PubMed
1993
Molecular analysis of spv virulence genes of the Salmonella virulence plasmids.
Molecular microbiology. 7(6):825-30 [PMID] 8483415.
View on: PubMed
1993
The Salmonella typhimurium virulence plasmid increases the growth rate of salmonellae in mice.
Infection and immunity. 61(2):504-11 [PMID] 8423080.
View on: PubMed
1993
Use of incompatible plasmids to control expression of antigen by Salmonella typhimurium and analysis of immunogenicity in mice.
Microbial pathogenesis. 15(2):93-101 [PMID] 8255210.
View on: PubMed
1992
Identification, genetic analysis and DNA sequence of a 7.8-kb virulence region of the Salmonella typhimurium virulence plasmid.
Molecular microbiology. 6(10):1395-411 [PMID] 1322485.
View on: PubMed
1991
The Salmonella typhimurium virulence plasmid encodes a positive regulator of a plasmid-encoded virulence gene.
Journal of bacteriology. 173(22):7176-85 [PMID] 1657882.
View on: PubMed
1990
Genetic and DNA sequence analysis of the Salmonella typhimurium virulence plasmid gene encoding the 28,000-molecular-weight protein.
Infection and immunity. 58(8):2651-8 [PMID] 2164511.
View on: PubMed
1990
Virulence plasmids of Salmonella typhimurium and other salmonellae.
Microbial pathogenesis. 8(1):3-11 [PMID] 2185396.
View on: PubMed
1989
Stable recombinant avirulent Salmonella vaccine strains.
Advances in experimental medicine and biology. 251:33-47 [PMID] 2692430.
View on: PubMed
1989
Selective delivery of antigens by recombinant bacteria.
Current topics in microbiology and immunology. 146:35-49 [PMID] 2659274.
View on: PubMed
1989
Antigenic evidence for simultaneous expression of two different lipooligosaccharides by some strains of Haemophilus influenzae type b.
Infection and immunity. 57(7):1971-8 [PMID] 2786504.
View on: PubMed
1989
Hybridization studies with a DNA probe derived from the virulence region of the 60 Mdal plasmid of Salmonella typhimurium.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire. 53(4):378-84 [PMID] 2686827.
View on: PubMed
1988
Cloning and transposon insertion mutagenesis of virulence genes of the 100-kilobase plasmid of Salmonella typhimurium.
Infection and immunity. 56(12):3262-71 [PMID] 2846443.
View on: PubMed
1987
Conservation of epitopes in the oligosaccharide portion of the lipooligosaccharide of Haemophilus influenzae type b.
Infection and immunity. 55(3):513-20 [PMID] 2434425.
View on: PubMed
1987
Plasmid-associated virulence of Salmonella typhimurium.
Infection and immunity. 55(12):2891-901 [PMID] 3316027.
View on: PubMed
1985
A minor high-molecular-weight outer membrane protein of Haemophilus influenzae type b is a protective antigen.
Infection and immunity. 47(1):253-9 [PMID] 2578121.
View on: PubMed
1985
Coprecipitation of lipopolysaccharide and the 39,000-molecular-weight major outer membrane protein of Haemophilus influenzae type b by lipopolysaccharide-directed monoclonal antibody.
Infection and immunity. 49(3):819-27 [PMID] 3875563.
View on: PubMed
1984
Immunogenic proteins in cell-free culture supernatants of Haemophilus influenzae type b.
Infection and immunity. 44(1):41-8 [PMID] 6368394.
View on: PubMed
1983
A set of two monoclonal antibodies specific for the cell surface-exposed 39K major outer membrane protein of Haemophilus influenzae type b defines all strains of this pathogen.
Infection and immunity. 42(2):516-24 [PMID] 6605924.
View on: PubMed
1983
Haemophilus influenzae type b disease after rifampin prophylaxis in a day care center: possible reasons for its failure.
Pediatric infectious disease. 2(3):193-8 [PMID] 6602974.
View on: PubMed
1982
Antibody response of infants to cell surface-exposed outer membrane proteins of Haemophilus influenzae type b after systemic Haemophilus disease.
Infection and immunity. 37(1):82-8 [PMID] 6980838.
View on: PubMed
1982
Immunoprotection of rats against Haemophilus influenzae type B disease mediated by monoclonal antibody against a haemophilus outer-membrane protein.
Lancet (London, England). 1(8268):366-8 [PMID] 6120351.
View on: PubMed
1982
Monoclonal antibodies directed against a cell surface-exposed outer membrane protein of Haemophilus influenzae type b.
Infection and immunity. 36(1):80-8 [PMID] 6176548.
View on: PubMed

Grants

Jul 2017 ACTIVE
Countering beta-lactam resistance in Pseudomonas aeruginosa
Role: Principal Investigator
Funding: NATL INST OF HLTH NIAID
Jun 2017 ACTIVE
Identification of Fecal Bacteria with Anti-Clostridium difficile Activities
Role: Principal Investigator
Funding: UF DSR OPPORTUNITY FUND
Aug 2014 – Aug 2020
Microbiology Research
Role: Principal Investigator
Funding: UF FOU

Teaching Profile

Courses Taught
2006-2007,2014-2021
GMS6121 Infectious Diseases
2015-2021
GMS7192 Journal Colloquy
2006-2013,2015-2021
GMS6038 Bacterial Genetics and Physiology
2016-2021
GMS6108 Bacterial Physiology, Antibiotics, and Genetics
2018-2021
GMS6153 Advanced Bacterial Genetics
2020-2021
BMS6634 GI and Hepatology
2020-2021
BMS6642 The Resp Sys Hlth
2013-2014,2016-2021,2020-2021
BMS6300 Fund Micro and Immuno
2019
GMS6169 Antimicrobial Strategies
2018
MCB7979 Advanced Research
2018
PLP7979 Advanced Research
2018
MCB7980 Research for Doctoral Dissertation
2018
VME7979 Advanced Research
2014-2016
GMS6140 Principles of Immunology
2016
GMS5905 Special Topics in Biomedical Sciences
2013-2014
GMS6003 Fundamentals of Graduate Research and Professional Development
2011-2014
GMS6090 Research in Medical Sciences
2012-2014
BMS4905 Medical Sciences Senior Research
2011-2014
GMS7979 Advanced Research
2011-2014
GMS7980 Research for Doctoral Dissertation
2011-2014
GMS6910 Supervised Research
2011-2014
GMS6905 Independent Studies in Medical Sciences
2011-2014
GMS6971 Research for Master’s Thesis
2011-2012
GMS6001 Fundamentals of Biomedical Sciences I
2007-2008,2010-2012
BMS6300C Med Micrbio/Infec Dis

Contact Details

Phones:
Business:
(352) 294-5544
Emails:
Business:
gulig@ufl.edu