Shouguang Jin,
Professor
Teaching Profile
Courses Taught
2020-2021
GMS6169 Antimicrobial Strategies
2020-2021
GMS6132 Introductory Gene and Immunotherapy
2016-2021
GMS6108 Bacterial Physiology, Antibiotics, and Genetics
2013,2016-2019,2019
GMS6153 Advanced Bacterial Genetics
2019
GMS6506 Biologic Drug Development
2018
CHM7980 Research for Doctoral Dissertation
2018
CHM7979 Advanced Research
2018
BMS6300 Fund Micro and Immuno
2014-2016
GMS6331 Stem Cell Biology
2016
GMS5905 Special Topics in Biomedical Sciences
2008,2010-2014,2014
GMS6121 Infectious Diseases
2006-2011
GMS7191 Research Conference
2008-2011
GMS6198 Bacterial Pathogenesis Journal Club
2006-2007
GMS7192 Journal Colloquy
2006-2007
GMS6181 Spec Topics Microbiol
Publications
2023
Design, Synthesis, and Evaluation of Carbonate-Linked Halogenated Phenazine-Quinone Prodrugs with Improved Water-Solubility and Potent Antibacterial Profiles.
ACS infectious diseases.
9(4):899-915
[DOI] 10.1021/acsinfecdis.2c00558.
[PMID] 36867688.
2023
Molecular testing devices for on-site detection of E. coli in water samples.
Scientific reports.
13(1)
[DOI] 10.1038/s41598-023-31208-4.
[PMID] 36918634.
2022
Complex Evaluation of Surfactant Protein A and D as Biomarkers for the Severity of COPD.
International journal of chronic obstructive pulmonary disease.
17:1537-1552
[DOI] 10.2147/COPD.S366988.
[PMID] 35811742.
2022
In situ self-assembled peptide enables effective cancer immunotherapy by blockage of CD47.
Colloids and surfaces. B, Biointerfaces.
217
[DOI] 10.1016/j.colsurfb.2022.112655.
[PMID] 35785715.
2022
Modular Synthetic Routes to Fluorine-Containing Halogenated Phenazine and Acridine Agents That Induce Rapid Iron Starvation in Methicillin-Resistant Staphylococcus aureus Biofilms.
ACS infectious diseases.
8(2):280-295
[DOI] 10.1021/acsinfecdis.1c00402.
[PMID] 35089005.
2022
Transcript Profiling of Nitroxoline-Treated Biofilms Shows Rapid Up-regulation of Iron Acquisition Gene Clusters.
ACS infectious diseases.
8(8):1594-1605
[DOI] 10.1021/acsinfecdis.2c00206.
[PMID] 35830188.
2021
A Modular Synthetic Route Involving N-Aryl-2-nitrosoaniline Intermediates Leads to a New Series of 3-Substituted Halogenated Phenazine Antibacterial Agents.
Journal of medicinal chemistry.
64(11):7275-7295
[DOI] 10.1021/acs.jmedchem.1c00168.
[PMID] 33881312.
2021
An ether-linked halogenated phenazine-quinone prodrug model for antibacterial applications.
Organic & biomolecular chemistry.
19(30):6603-6608
[DOI] 10.1039/d1ob01107c.
[PMID] 34286808.
2021
Design, synthesis and biological evaluation of a halogenated phenazine-erythromycin conjugate prodrug for antibacterial applications.
Organic & biomolecular chemistry.
19(7):1483-1487
[DOI] 10.1039/d0ob02428g.
[PMID] 33521803.
2020
High-efficiency protein delivery into transfection-recalcitrant cell types.
Biotechnology and bioengineering.
117(3):816-831
[DOI] 10.1002/bit.27245.
[PMID] 31814110.
2020
Molecular genetic analysis of an XDR Pseudomonas aeruginosa ST664 clone carrying multiple conjugal plasmids.
The Journal of antimicrobial chemotherapy.
75(6):1443-1452
[DOI] 10.1093/jac/dkaa063.
[PMID] 32129854.
2020
PvrA is a novel regulator that contributes to Pseudomonas aeruginosa pathogenesis by controlling bacterial utilization of long chain fatty acids.
Nucleic acids research.
48(11):5967-5985
[DOI] 10.1093/nar/gkaa377.
[PMID] 32406921.
2020
TpiA is a Key Metabolic Enzyme That Affects Virulence and Resistance to Aminoglycoside Antibiotics through CrcZ in Pseudomonas aeruginosa.
mBio.
11(1)
[DOI] 10.1128/mBio.02079-19.
[PMID] 31911486.
2019
Pseudomonas aeruginosa ExsA regulates a metalloprotease ImpA that inhibits phagocytosis of macrophages
Infection and Immunity.
87(12)
[DOI] 10.1128/IAI.00695-19.
[PMID] 31527124.
2019
Combination of Azithromycin and Gentamicin for Efficient Treatment of Pseudomonas aeruginosa Infections.
The Journal of infectious diseases.
220(10):1667-1678
[DOI] 10.1093/infdis/jiz341.
[PMID] 31419286.
2019
Identification of a small RNA that directly controls the translation of the quorum sensing signal synthase gene rhlI in Pseudomonas aeruginosa.
Environmental microbiology.
21(8):2933-2947
[DOI] 10.1111/1462-2920.14686.
[PMID] 31106966.
2019
Mechanisms of RsaL mediated tolerance to ciprofloxacin and carbenicillin in Pseudomonas aeruginosa.
Current genetics.
65(1):213-222
[DOI] 10.1007/s00294-018-0863-3.
[PMID] 29951698.
2019
NrtR Regulates the Type III Secretion System Through cAMP/Vfr Pathway in Pseudomonas aeruginosa.
Frontiers in microbiology.
10
[DOI] 10.3389/fmicb.2019.00085.
[PMID] 30761117.
2019
Oligoribonuclease Contributes to Tolerance to Aminoglycoside and β-Lactam Antibiotics by Regulating KatA in Pseudomonas aeruginosa.
Antimicrobial agents and chemotherapy.
63(6)
[DOI] 10.1128/AAC.00212-19.
[PMID] 30936107.
2019
Pseudomonas aeruginosa Polynucleotide Phosphorylase Contributes to Ciprofloxacin Resistance by Regulating PrtR.
Frontiers in microbiology.
10
[DOI] 10.3389/fmicb.2019.01762.
[PMID] 31417536.
2019
The Pseudomonas aeruginosa HSP70-like protein DnaK induces IL-1β expression via TLR4-dependent activation of the NF-κB and JNK signaling pathways
Comparative Immunology, Microbiology, & Infectious Diseases.
67
[DOI] 10.1016/j.cimid.2019.101373.
[PMID] 31704499.
2018
A Rapid Phenotypic Whole-Cell Screening Approach for the Identification of Small-Molecule Inhibitors That Counter β-Lactamase Resistance in Pseudomonas aeruginosa.
SLAS discovery : advancing life sciences R & D.
23(1):55-64
[DOI] 10.1177/2472555217728489.
[PMID] 28850797.
2018
An Efficient Buchwald-Hartwig/Reductive Cyclization for the Scaffold Diversification of Halogenated Phenazines: Potent Antibacterial Targeting, Biofilm Eradication, and Prodrug Exploration.
Journal of medicinal chemistry.
61(9):3962-3983
[DOI] 10.1021/acs.jmedchem.7b01903.
[PMID] 29638121.
2018
Bacterial type III secretion system as a protein delivery tool for a broad range of biomedical applications.
Biotechnology advances.
36(2):482-493
[DOI] 10.1016/j.biotechadv.2018.01.016.
[PMID] 29409784.
2018
Construction of a Protective Vaccine Against Lipopolysaccharide-Heterologous Pseudomonas aeruginosa Strains Based on Expression Profiling of Outer Membrane Proteins During Infection.
Frontiers in immunology.
9
[DOI] 10.3389/fimmu.2018.01737.
[PMID] 30093906.
2018
Enhanced Differentiation of Human Pluripotent Stem Cells Into Cardiomyocytes By Bacteria-Mediated Transcription Factors Delivery
PLoS One.
13(3)
[DOI] 10.1371/journal.pone.0194895.
[PMID] 29579079.
2018
Halogenated quinolines bearing polar functionality at the 2-position: Identification of new antibacterial agents with enhanced activity against Staphylococcus epidermidis.
European journal of medicinal chemistry.
155:705-713
[DOI] 10.1016/j.ejmech.2018.06.045.
[PMID] 29936357.
2018
HigB Reciprocally Controls Biofilm Formation and the Expression of Type III Secretion System Genes through Influencing the Intracellular c-di-GMP Level in Pseudomonas aeruginosa
Toxins.
10(11)
[DOI] 10.3390/toxins10110424.
[PMID] 30355991.
2018
PA5470 Counteracts Antimicrobial Effect of Azithromycin by Releasing Stalled Ribosome in Pseudomonas aeruginosa.
Antimicrobial agents and chemotherapy.
62(2)
[DOI] 10.1128/AAC.01867-17.
[PMID] 29203495.
2018
PutA Is Required for Virulence and Regulated by PruR in Pseudomonas aeruginosa.
Frontiers in microbiology.
9
[DOI] 10.3389/fmicb.2018.00548.
[PMID] 29632523.
2018
Regulatory protein SrpA controls phage infection and core cellular processes in Pseudomonas aeruginosa.
Nature communications.
9(1)
[DOI] 10.1038/s41467-018-04232-6.
[PMID] 29748556.
2018
Transcript Profiling of MRSA Biofilms Treated with a Halogenated Phenazine Eradicating Agent: A Platform for Defining Cellular Targets and Pathways Critical to Biofilm Survival.
Angewandte Chemie (International ed. in English).
57(47):15523-15528
[DOI] 10.1002/anie.201809785.
[PMID] 30230671.
2017
A Highly Potent Class of Halogenated Phenazine Antibacterial and Biofilm-Eradicating Agents Accessed Through a Modular Wohl-Aue Synthesis.
Scientific reports.
7(1)
[DOI] 10.1038/s41598-017-01045-3.
[PMID] 28515440.
2017
Fis Regulates Type III Secretion System by Influencing the Transcription of exsA in Pseudomonas aeruginosa Strain PA14.
Frontiers in microbiology.
8
[DOI] 10.3389/fmicb.2017.00669.
[PMID] 28469612.
2017
In Vivo Host Environment Alters Pseudomonas Aeruginosa Susceptibility to Aminoglycoside Antibiotics
Frontiers in Cellular and Infection Microbiology.
7
[DOI] 10.3380/fcimb.2017.00083.
2017
Suhb Regulates the Motile-Sessile Switch in Pseudomonas Aeruginosa Through the Gac/Rsm Pathway and C-Di-Gmp Signaling
Frontiers in microbiology.
8
[DOI] 10.3389/fmicb.2017.01045.
[PMID] 28642753.
2016
Epidemiological Characterization of Acinetobacter Baumannii Bloodstream Isolates From a Chinese Burn Institute: a Three-Year Study
Burns.
42(7):1542-1547
[DOI] 10.1016/j.burns.2016.02.021.
2016
Identification of D-amino acid dehydrogenase as an upstream regulator of the autoinduction of a putative acyltransferase in Corynebacterium glutamicum
Journal of Microbiology.
54(6):432-9
[DOI] 10.1007/s12275-016-6046-3.
[PMID] 27225460.
2016
Oligoribonuclease Is Required for the Type III Secretion System and Pathogenesis of Pseudomonas Aeruginosa
Microbiological Research.
188:90-96
[DOI] 10.1016/j.micres.2016.05.002.
2016
PA3297 Counteracts Antimicrobial Effects of Azithromycin in Pseudomonas aeruginosa
Frontiers in Microbiology.
7
[DOI] 10.3389/fmicb.2016.00317.
[PMID] 27014238.
2016
Polynucleotide Phosphorylase Regulates Multiple Virulence Factors and the Stabilities of Small RNAs RsmY/Z in Pseudomonas aeruginosa.
Frontiers in microbiology.
7
[DOI] 10.3389/fmicb.2016.00247.
[PMID] 26973625.
2016
Pseudomonas Aeruginosa Enolase Influences Bacterial Tolerance to Oxidative Stresses and Virulence
Frontiers in microbiology.
7
[DOI] 10.3389/fmicb.2016.01999.
[PMID] 28018326.
2016
Structure-Activity Relationships of a Diverse Class of Halogenated Phenazines That Targets Persistent, Antibiotic-Tolerant Bacterial Biofilms and Mycobacterium tuberculosis.
Journal of medicinal chemistry.
59(8):3808-25
[DOI] 10.1021/acs.jmedchem.5b02004.
[PMID] 27018907.
2016
Structure-Function Analysis of the Transmembrane Protein AmpG from Pseudomonas aeruginosa.
PloS one.
11(12)
[DOI] 10.1371/journal.pone.0168060.
[PMID] 27959942.
2016
Synthetically Tuning the 2-Position of Halogenated Quinolines: Optimizing Antibacterial and Biofilm Eradication Activities via Alkylation and Reductive Amination Pathways.
Chemistry (Weinheim an der Bergstrasse, Germany).
22(27):9181-9
[DOI] 10.1002/chem.201600926.
[PMID] 27245927.
2016
TatC-dependent translocation of pyoverdine is responsible for the microbial growth suppression.
Journal of microbiology (Seoul, Korea).
54(2):122-30
[DOI] 10.1007/s12275-016-5542-9.
[PMID] 26832668.
2015
A Phytochemical-Halogenated Quinoline Combination Therapy Strategy for the Treatment of Pathogenic Bacteria.
ChemMedChem.
10(7):1157-62
[DOI] 10.1002/cmdc.201500179.
[PMID] 25982664.
2015
A practical guide to induced pluripotent stem cell research using patient samples.
Laboratory investigation; a journal of technical methods and pathology.
95(1):4-13
[DOI] 10.1038/labinvest.2014.104.
[PMID] 25089770.
2015
Bromophenazine Derivatives With Potent Inhibition, Dispersion and Eradication Activities Against Staphylococcus Aureus Biofilms
Rsc Advances.
5(2):1120-1124
[DOI] 10.1039/c4ra08728c.
2015
Directed Differentiation of Embryonic Stem Cells Into Cardiomyocytes by Bacterial Injection of Defined Transcription Factors.
Scientific reports.
5
[DOI] 10.1038/srep15014.
[PMID] 26449528.
2015
Efficient Gene Editing in Pluripotent Stem Cells by Bacterial Injection of Transcription Activator-Like Effector Nuclease Proteins.
Stem cells translational medicine.
4(8):913-26
[DOI] 10.5966/sctm.2015-0030.
[PMID] 26062981.
2015
Expression and Efficient Purification of Tag-Cleaved Active Recombinant Human Insulin-Like Growth Factor-II From Escherichia Coli
Biotechnology and Bioprocess Engineering.
20(2):234-241
[DOI] 10.1007/s12257-014-0562-y.
2015
Genome modification leads to phenotype reversal in human myotonic dystrophy type 1 induced pluripotent stem cell-derived neural stem cells.
Stem cells (Dayton, Ohio).
33(6):1829-38
[DOI] 10.1002/stem.1970.
[PMID] 25702800.
2015
Halogenated Phenazines that Potently Eradicate Biofilms, MRSA Persister Cells in Non-Biofilm Cultures, and Mycobacterium tuberculosis.
Angewandte Chemie (International ed. in English).
54(49):14819-23
[DOI] 10.1002/anie.201508155.
[PMID] 26480852.
2015
Optimization of a miniaturized fluid array device for cell-free protein synthesis.
Biotechnology and bioengineering.
112(12):2459-67
[DOI] 10.1002/bit.25668.
[PMID] 26037852.
2015
SuhB is a novel ribosome associated protein that regulates expression of MexXY by modulating ribosome stalling in Pseudomonas aeruginosa.
Molecular microbiology.
98(2):370-83
[DOI] 10.1111/mmi.13126.
[PMID] 26179141.
2014
A Novel Pseudomonas Aeruginosa-Derived Effector Cooperates With Flagella To Mediate the Upregulation of Interleukin 8 in Human Epithelial Cells
Microbial Pathogenesis.
66:24-28
[DOI] 10.1016/j.micpath.2013.12.001.
[PMID] 24361345.
2014
Bacterial Delivery of Talen Proteins for Human Genome Editing
PLoS One.
9(3)
[DOI] 10.1371/journal.pone.0091547.
[PMID] 24618838.
2014
Distinct roles of major peptidoglycan recycling enzymes in β-Lactamase production in Shewanella oneidensis.
Antimicrobial agents and chemotherapy.
58(11):6536-43
[DOI] 10.1128/AAC.03238-14.
[PMID] 25136029.
2014
Nucleoside diphosphate kinase and flagellin from Pseudomonas aeruginosa induce interleukin 1 expression via the Akt/NF-κB signaling pathways.
Infection and immunity.
82(8):3252-60
[DOI] 10.1128/IAI.02007-14.
[PMID] 24866792.
2014
Phenazine antibiotic inspired discovery of potent bromophenazine antibacterial agents against Staphylococcus aureus and Staphylococcus epidermidis.
Organic & biomolecular chemistry.
12(6):881-6
[DOI] 10.1039/c3ob42416b.
[PMID] 24389824.
2014
Prtr Homeostasis Contributes To Pseudomonas Aeruginosa Pathogenesis and Resistance Against Ciprofloxacin
Infection and Immunity.
82(4):1638-1647
[DOI] 10.1128/IAI.01388-13.
[PMID] 24491574.
2014
Pseudomonas aeruginosa injects NDK into host cells through a type III secretion system.
Microbiology (Reading, England).
160(Pt 7):1417-1426
[DOI] 10.1099/mic.0.078139-0.
[PMID] 24699069.
2014
Pseudomonas aeruginosa-induced IL-1β production is inhibited by Sophora flavescens via the NF-κB/inflammasome pathways.
Journal of microbiology (Seoul, Korea).
52(12):1044-9
[DOI] 10.1007/s12275-014-4512-3.
[PMID] 25467122.
2013
Development of a novel ex vivo porcine skin explant model for the assessment of mature bacterial biofilms.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.
21(5):704-14
[DOI] 10.1111/wrr.12074.
[PMID] 23927831.
2013
Direct reprogramming of fibroblasts to myocytes via bacterial injection of MyoD protein.
Cellular reprogramming.
15(2):117-25
[DOI] 10.1089/cell.2012.0058.
[PMID] 23438194.
2013
High level expression, efficient purification and bioactivity assay of recombinant human platelet-derived growth factor AA dimer (PDGF-AA) from methylotrophic yeast Pichia pastoris.
Protein expression and purification.
91(2):221-7
[DOI] 10.1016/j.pep.2013.08.008.
[PMID] 23978536.
2013
SuhB is a regulator of multiple virulence genes and essential for pathogenesis of Pseudomonas aeruginosa.
mBio.
4(6):e00419-13
[DOI] 10.1128/mBio.00419-13.
[PMID] 24169572.
2013
The reprogrammed pancreatic progenitor-like intermediate state of hepatic cells is more susceptible to pancreatic beta cell differentiation.
Journal of cell science.
126(Pt 16):3638-48
[DOI] 10.1242/jcs.124925.
[PMID] 23750005.
2012
6-Bromo-1,3-benzothia-zol-2-amine.
Acta crystallographica. Section E, Structure reports online.
68(Pt 10)
[DOI] 10.1107/S1600536812040123.
[PMID] 23125786.
2012
B Segregation To Grain Boundaries and Diffusion in Polycrystalline Si With Flash Annealing
Journal of Applied Physics.
111(4)
[DOI] 10.1063/1.3688246.
2012
Bioinformatic analysis of the Acinetobacter baumannii phage AB1 genome.
Gene.
507(2):125-34
[DOI] 10.1016/j.gene.2012.07.029.
[PMID] 22868206.
2012
BMS309403 stimulates glucose uptake in myotubes through activation of AMP-activated protein kinase.
PloS one.
7(8)
[DOI] 10.1371/journal.pone.0044570.
[PMID] 22952994.
2012
Gene Identification in Pseudomonas Aeruginosa: From Bioinformatics To Experimental Analysis
The FASEB's Journal.
26
2012
High Level Expression, Purification and Characterization of Active Fusion Human C1Q and Tumor Necrosis Factor Related Protein 2 (Hctrp2) in Escherichia Coli (Vol 79, Pg 1, 2011)
Protein Expression and Purification.
82(1)
[DOI] 10.1016/j.pep.2011.11.005.
2012
The Pseudomonas aeruginosa type III secretion system has an exotoxin S/T/Y independent pathogenic role during acute lung infection.
PloS one.
7(7)
[DOI] 10.1371/journal.pone.0041547.
[PMID] 22844497.
2011
Autoinduction of a genetic locus encoding putative acyltransferase in Corynebacterium glutamicum.
Biotechnology letters.
33(1):97-102
[DOI] 10.1007/s10529-010-0395-5.
[PMID] 20821248.
2011
Bacterial delivery of nuclear proteins into pluripotent and differentiated cells.
PloS one.
6(1)
[DOI] 10.1371/journal.pone.0016465.
[PMID] 21304583.
2011
High Level Expression of Active Recombinant Human Interleukin-3 in Pichia Pastoris
Protein Expression and Purification.
80(2):185-193
[DOI] 10.1016/j.pep.2011.08.027.
[PMID] 21907288.
2011
High level expression, purification and characterization of active fusion human C1q and tumor necrosis factor related protein 2 (hCTRP2) in Escherichia coli.
Protein expression and purification.
79(1):1-6
[DOI] 10.1016/j.pep.2011.03.013.
[PMID] 21453774.
2011
Interface Stability in Stressed Solid-Phase Epitaxial Growth
Journal of Vacuum Science & Technology B.
29(4)
[DOI] 10.1116/1.3610172.
2011
Large-Scale Production, Purification and Bioactivity Assay of Recombinant Human Interleukin-6 in the Methylotrophic Yeast Pichia Pastoris
Fems Yeast Research.
11(2):160-167
[DOI] 10.1111/j.1567-1364.2010.00701.x.
[PMID] 21176103.
2011
MexT regulates the type III secretion system through MexS and PtrC in Pseudomonas aeruginosa.
Journal of bacteriology.
193(2):399-410
[DOI] 10.1128/JB.01079-10.
[PMID] 21075931.
2011
Mutation of pfm affects the adherence of Pseudomonas aeruginosa to host cells and the quorum sensing system.
FEMS microbiology letters.
324(2):173-80
[DOI] 10.1111/j.1574-6968.2011.02401.x.
[PMID] 22092819.
2011
N-glycosylation augmentation of the cystic fibrosis epithelium improves Pseudomonas aeruginosa clearance.
American journal of respiratory cell and molecular biology.
44(6):824-30
[DOI] 10.1165/rcmb.2009-0285OC.
[PMID] 20693405.
2011
Pulsed-Laser Atom Probe Tomography of P-Type Field Effect Transistors On Si-On-Insulator Substrates
Journal of Vacuum Science & Technology B.
29(6)
[DOI] 10.1116/1.3647879.
2010
ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression.
Antimicrobial agents and chemotherapy.
54(11):4772-9
[DOI] 10.1128/AAC.00009-10.
[PMID] 20713660.
2010
Cell-free expression of soluble and membrane proteins in an array device for drug screening.
Analytical chemistry.
82(16):7021-6
[DOI] 10.1021/ac1015479.
[PMID] 20666430.
2010
Dopant Measurements in Semiconductors With Atom Probe Tomography
Journal of Vacuum Science & Technology B.
28(1):C1E1-C1E4
[DOI] 10.1116/1.3242422.
2010
Miniaturized fluid array for high-throughput protein expression.
Biotechnology progress.
26(6):1590-6
[DOI] 10.1002/btpr.474.
[PMID] 20661923.
2010
MKP1 regulates the induction of inflammatory response by pneumococcal pneumolysin in human epithelial cells.
FEMS immunology and medical microbiology.
60(2):171-8
[DOI] 10.1111/j.1574-695X.2010.00733.x.
[PMID] 20868379.
2010
Mkp1 Regulates the Induction of Mcp1 By Streptococcus Pneumoniae Pneumolysin in Human Epithelial Cells
Molecules and Cells.
30(3):263-270
[DOI] 10.1007/s10059-010-0113-0.
[PMID] 20803086.
2010
Role of pneumococcal pneumolysin in the induction of an inflammatory response in human epithelial cells.
FEMS immunology and medical microbiology.
60(1):28-35
[DOI] 10.1111/j.1574-695X.2010.00699.x.
[PMID] 20528932.
2010
Sensitive detection of multiplex toxins using antibody microarray.
Analytical biochemistry.
401(2):271-9
[DOI] 10.1016/j.ab.2010.02.040.
[PMID] 20226158.
2010
Sequence Analysis of Pkf3-70 in Klebsiella Pneumoniae: Probable Origin From R100-Like Plasmid of Escherichia Coli
PLoS One.
5(1)
[DOI] 10.1371/journal.pone.0008601.
[PMID] 20066042.
2009
Expression, purification, and functional characterization of recombinant human interleukin-7.
Protein expression and purification.
63(1):1-4
[DOI] 10.1016/j.pep.2008.08.009.
[PMID] 18805490.
2009
High level expression and purification of active recombinant human interleukin-8 in Pichia pastoris.
Protein expression and purification.
68(1):60-4
[DOI] 10.1016/j.pep.2009.06.010.
[PMID] 19545634.
2008
A systematic survey of mini-proteins in bacteria and archaea.
PloS one.
3(12)
[DOI] 10.1371/journal.pone.0004027.
[PMID] 19107199.
2008
Effect of Carbon Codoping On Boron Diffusion in Amorphous Silicon
Applied Physics Letters.
93(7)
[DOI] 10.1063/1.2975833.
2008
Functional characterization of MigA and WapR: putative rhamnosyltransferases involved in outer core oligosaccharide biosynthesis of Pseudomonas aeruginosa.
Journal of bacteriology.
190(6):1857-65
[DOI] 10.1128/JB.01546-07.
[PMID] 18178733.
2008
Mkp1 Regulates the Induction of Muc5Ac Mucin By Streptococcus Pneumoniae Pneumolysin By Inhibiting the Pak4-Jnk Signaling Pathway
Journal of Biological Chemistry.
283(45):30624-30631
[DOI] 10.1074/jbc.M802519200.
[PMID] 18782768.
2008
The Pseudomonas aeruginosa Type III secretion system plays a dual role in the regulation of caspase-1 mediated IL-1beta maturation.
Journal of cellular and molecular medicine.
12(5A):1767-76
[PMID] 18081695.
2007
Regulatory role of PopN and its interacting partners in type III secretion of Pseudomonas aeruginosa.
Journal of bacteriology.
189(7):2599-609
[PMID] 17237176.
2006
ExoS of Pseudomonas aeruginosa induces apoptosis through a Fas receptor/caspase 8-independent pathway in HeLa cells.
Cellular microbiology.
8(2):326-38
[PMID] 16441442.
2006
Expression of Pseudomonas aeruginosa toxin ExoS effectively induces apoptosis in host cells.
Infection and immunity.
74(12):6557-70
[PMID] 16966406.
2006
Ricin detection by biological signal amplification in a well-in-a-well device.
Analytical chemistry.
78(22):7659-64
[PMID] 17105156.
2005
Factors triggering type III secretion in Pseudomonas aeruginosa.
Microbiology (Reading, England).
151(Pt 11):3575-3587
[DOI] 10.1099/mic.0.28277-0.
[PMID] 16272380.
2005
PtrB of Pseudomonas aeruginosa suppresses the type III secretion system under the stress of DNA damage.
Journal of bacteriology.
187(17):6058-68
[PMID] 16109947.
2005
Toxin detection by a miniaturized in vitro protein expression array.
Analytical chemistry.
77(17):5494-500
[PMID] 16131058.
2004
A rapid bioassay for single bacterial cell quantitation using bioconjugated nanoparticles.
Proceedings of the National Academy of Sciences of the United States of America.
101(42):15027-32
[PMID] 15477593.
2004
An in vivo inducible gene of Pseudomonas aeruginosa encodes an anti-ExsA to suppress the type III secretion system.
Molecular microbiology.
54(2):307-20
[PMID] 15469505.
2004
Crystallization and preliminary X-ray crystallographic studies on recombinant rat choline acetyltransferase.
Acta crystallographica. Section D, Biological crystallography.
60(Pt 2):374-5
[PMID] 14747730.
2004
MucA-mediated coordination of type III secretion and alginate synthesis in Pseudomonas aeruginosa.
Journal of bacteriology.
186(22):7575-85
[PMID] 15516570.
2004
Mutants of Agrobacterium tumefaciens virG gene that activate transcription of vir promoter in Escherichia coli.
Current microbiology.
49(5):334-40
[PMID] 15486707.
2004
Structural and mutational characterization of L-carnitine binding to human carnitine acetyltransferase.
Journal of structural biology.
146(3):416-24
[PMID] 15099582.
2004
Structural insights and functional implications of choline acetyltransferase.
Journal of structural biology.
148(2):226-35
[PMID] 15477102.
2004
Ultrasensitive detection of biomolecules with fluorescent dye-doped nanoparticles.
Analytical biochemistry.
334(1):135-44
[PMID] 15464962.
2003
aph(3′)-IIb, a gene encoding an aminoglycoside-modifying enzyme, is under the positive control of surrogate regulator HpaA.
Antimicrobial agents and chemotherapy.
47(12):3867-76
[PMID] 14638496.
2003
c-Jun NH2-terminal kinase-mediated signaling is essential for Pseudomonas aeruginosa ExoS-induced apoptosis.
Infection and immunity.
71(6):3361-70
[PMID] 12761120.
2003
DsbA of Pseudomonas aeruginosa is essential for multiple virulence factors.
Infection and immunity.
71(3):1590-5
[PMID] 12595484.
2003
Regulation of membrane permeability by a two-component regulatory system in Pseudomonas aeruginosa.
Antimicrobial agents and chemotherapy.
47(1):95-101
[PMID] 12499175.
2000
migA, a quorum-responsive gene of Pseudomonas aeruginosa, is highly expressed in the cystic fibrosis lung environment and modifies low-molecular-mass lipopolysaccharide.
Microbiology (Reading, England).
146 ( Pt 10):2509-2519
[DOI] 10.1099/00221287-146-10-2509.
[PMID] 11021926.
Grants
Sep 2017
– Aug 2018
Optimizing systemic stem/progenitor cell therapy for AMD
Role: Co-Investigator
Funding: UNIV OF ALABAMA BIRMINGHAM
via NATL INST OF HLTH NEI
Jul 2016
– Sep 2020
A stem cell tactic to promote personalized medicine
Role: Project Manager
Funding: NATL INST OF HLTH NIGMS
Jul 2015
– Jun 2017
Countering beta-lactam resistance in Pseudomonas aeruginosa
Role: Principal Investigator
Funding: NATL INST OF HLTH NIAID
Jun 2014
– May 2016
Development of Potent 2,4-Dibromophenazine Antibacterial Antibiofilm Agents
Role: Project Manager
Funding: UF DSR OPPORTUNITY FUND
Jul 2013
– Aug 2017
Role of CX3CR1 and CCR2 in controlling microglia and mononuclear cells in AMD
Role: Project Manager
Funding: INDIANA UNIV
via NATL INST OF HLTH
Jul 2007
– Aug 2016
Clinical and Translational Science Institute
Role: Project Manager
Funding: UF RESEARCH FOU
Contact Details
Phones:
- Business:
- (352) 273-5973
Emails:
- Business:
- sjin@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100266
GAINESVILLE FL 32610 - Business Street:
-
R1-293, ARB
GAINESVILLE FL 326100266